Cargando…

NAD Modulates DNA Methylation and Cell Differentiation

Nutritional intake impacts the human epigenome by directing epigenetic pathways in normal cell development via as yet unknown molecular mechanisms. Consequently, imbalance in the nutritional intake is able to dysregulate the epigenetic profile and drive cells towards malignant transformation. Here w...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ummarino, Simone, Hausman, Clinton, Gaggi, Giulia, Rinaldi, Lucrezia, Bassal, Mahmoud A., Zhang, Yanzhou, Seelam, Andy Joe, Kobayashi, Ikei S., Borchiellini, Marta, Ebralidze, Alexander K., Ghinassi, Barbara, Trinh, Bon Q., Kobayashi, Susumu S., Di Ruscio, Annalisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616462/ https://www.ncbi.nlm.nih.gov/pubmed/34831209 http://dx.doi.org/10.3390/cells10112986

Ejemplares similares

Targeted systematic evolution of an RNA platform neutralizing DNMT1 function and controlling DNA methylation
por: Esposito, Carla L., et al.
Publicado: (2023)

The PARP Way to Epigenetic Changes
por: Ummarino, Simone, et al.
Publicado: (2021)

The Bright and Dark Side of DNA Methylation: A Matter of Balance
por: Borchiellini, Marta, et al.
Publicado: (2019)

Scavenging of Labile Heme by Hemopexin Is a Key Checkpoint in Cancer Growth and Metastases
por: Canesin, Giacomo, et al.
Publicado: (2020)

Application of Induced Pluripotent Stem Cell Technology to the Study of Hematological Diseases
por: Li, Mailin, et al.
Publicado: (2017)

Editorial: DNA methylation: The aging clock
por: Ghinassi, Barbara, et al.
Publicado: (2023)

Epigenetic Features of Human Perinatal Stem Cells Redefine Their Stemness Potential
por: Gaggi, Giulia, et al.
Publicado: (2020)

Preclinical Characterization of Mobocertinib Highlights the Putative Therapeutic Window of This Novel EGFR Inhibitor to EGFR Exon 20 Insertion Mutations
por: Vasconcelos, Pedro E.N.S., et al.
Publicado: (2020)

EGFR-D770>GY and Other Rare EGFR Exon 20 Insertion Mutations with a G770 Equivalence Are Sensitive to Dacomitinib or Afatinib and Responsive to EGFR Exon 20 Insertion Mutant-Active Inhibitors in Preclinical Models and Clinical Scenarios
por: Kobayashi, Ikei S., et al.
Publicado: (2021)

Human-Induced Pluripotent Stem Cell Technology and Cardiomyocyte Generation: Progress and Clinical Applications
por: Di Baldassarre, Angela, et al.
Publicado: (2018)

The Effects of Combined Exposure to Bisphenols and Perfluoroalkyls on Human Perinatal Stem Cells and the Potential Implications for Health Outcomes
por: Di Credico, Andrea, et al.
Publicado: (2023)

Spare Parts from Discarded Materials: Fetal Annexes in Regenerative Medicine
por: Gaggi, Giulia, et al.
Publicado: (2019)

Chemical and Biological Molecules Involved in Differentiation, Maturation, and Survival of Dopaminergic Neurons in Health and Parkinson’s Disease: Physiological Aspects and Clinical Implications
por: Gaggi, Giulia, et al.
Publicado: (2021)

Human mesenchymal amniotic fluid stem cells reveal an unexpected neuronal potential differentiating into functional spinal motor neurons
por: Gaggi, Giulia, et al.
Publicado: (2022)

Styryl Quinazolinones as Potential Inducers of Myeloid Differentiation via Upregulation of C/EBPα
por: Sridhar, Radhakrishnan, et al.
Publicado: (2018)

Bioelectrical Impedance Vector Analysis of Young Elite Team Handball Players
por: Di Credico, Andrea, et al.
Publicado: (2021)

Human Mesenchymal Stromal Cells Unveil an Unexpected Differentiation Potential toward the Dopaminergic Neuronal Lineage
por: Gaggi, Giulia, et al.
Publicado: (2020)

Human fetal membrane-mesenchymal stromal cells generate functional spinal motor neurons in vitro
por: Gaggi, Giulia, et al.
Publicado: (2022)

Real-Time Monitoring of Levetiracetam Effect on the Electrophysiology of an Heterogenous Human iPSC-Derived Neuronal Cell Culture Using Microelectrode Array Technology
por: Di Credico, Andrea, et al.
Publicado: (2021)

The Influence of Maturity Status on Anthropometric Profile and Body Composition of Youth Goalkeepers
por: Di Credico, Andrea, et al.
Publicado: (2020)

Immunohistochemical Results of Soft Tissues Around a New Implant Healing-Abutment Surface: A Human Study
por: Ghinassi, Barbara, et al.
Publicado: (2020)

Prognostic Value of High-Sensitivity Cardiac Troponin in Women
por: Bisaccia, Giandomenico, et al.
Publicado: (2022)

Impact on peri-implant connective tissue of laser treated versus traditional healing abutments: a human clinical trials
por: Gaggi, Giulia, et al.
Publicado: (2023)

“NAD-capQ” detection and quantitation of NAD caps
por: Grudzien-Nogalska, Ewa, et al.
Publicado: (2018)

An intrinsic purine metabolite AICAR blocks lung tumour growth by targeting oncoprotein mucin 1
por: Aftab, Fareesa, et al.
Publicado: (2023)

Metabolically distinct roles of NAD synthetase and NAD kinase define the essentiality of NAD and NADP in Mycobacterium tuberculosis
por: Sharma, Ritu, et al.
Publicado: (2023)

Cloning and Organelle Expression of Bamboo Mitochondrial Complex I Subunits Nad1, Nad2, Nad4, and Nad5 in the Yeast Saccharomyces cerevisiae
por: Tsai, Hsieh-Chin, et al.
Publicado: (2022)

NAD to the rescue
por: Tuma, Rabiya S.
Publicado: (2005)

Estimation of Heart Rate Variability Parameters by Machine Learning Approaches Applied to Facial Infrared Thermal Imaging
por: Di Credico, Andrea, et al.
Publicado: (2022)

NAD-seq for profiling the NAD(+) capped transcriptome of Arabidopsis thaliana
por: Yu, Xiang, et al.
Publicado: (2021)

NAD(+) Homeostasis and NAD(+)-Consuming Enzymes: Implications for Vascular Health
por: Campagna, Roberto, et al.
Publicado: (2023)

The Interplay between Dysregulated Metabolism and Epigenetics in Cancer
por: Bassal, Mahmoud Adel
Publicado: (2023)

Analysis of Individual Variations in Autonomic Responses to Urban and Forest Environments
por: Kobayashi, Hiromitsu, et al.
Publicado: (2015)

NAD(+) and Vascular Dysfunction: From Mechanisms to Therapeutic Opportunities
por: Abdellatif, Mahmoud, et al.
Publicado: (2022)

EGFR-A763_Y764insFQEA Is a Unique Exon 20 Insertion Mutation That Displays Sensitivity to Approved and In-Development Lung Cancer EGFR Tyrosine Kinase Inhibitors
por: Vasconcelos, Pedro E.N.S., et al.
Publicado: (2020)

The Prediction of Running Velocity during the 30–15 Intermittent Fitness Test Using Accelerometry-Derived Metrics and Physiological Parameters: A Machine Learning Approach
por: Di Credico, Andrea, et al.
Publicado: (2021)

DNMT1-interacting RNAs block gene specific DNA methylation
por: Di Ruscio, Annalisa, et al.
Publicado: (2013)

Quantification of localized NAD(+) changes reveals unique specificity of NAD(+) regulation in the hypothalamus
por: Johnson, Sean, et al.
Publicado: (2023)

Gingival Response to Dental Implant: Comparison Study on the Effects of New Nanopored Laser-Treated vs. Traditional Healing Abutments
por: Ghinassi, Barbara, et al.
Publicado: (2020)

Decellularized Extracellular Matrices and Cardiac Differentiation: Study on Human Amniotic Fluid-Stem Cells
por: Gaggi, Giulia, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_uvqviltmnk6urdgofh43guisku