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Impact of Chromatin Dynamics and DNA Repair on Genomic Stability and Treatment Resistance in Pediatric High-Grade Gliomas

SIMPLE SUMMARY: Pediatric high-grade gliomas (pHGGs) are the leading cause of mortality in pediatric neuro-oncology, due in great part to treatment resistance driven by complex DNA repair mechanisms. pHGGs have recently been divided into molecular subtypes based on mutations affecting the N-terminal...

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Detalles Bibliográficos
Autores principales:	Pinto, Lia, Baidarjad, Hanane, Entz-Werlé, Natacha, Van Dyck, Eric
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616465/ https://www.ncbi.nlm.nih.gov/pubmed/34830833 http://dx.doi.org/10.3390/cancers13225678

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