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ACLY Nuclear Translocation in Human Macrophages Drives Proinflammatory Gene Expression by NF-κB Acetylation

Macrophage stimulation by pathogen-associated molecular patterns (PAMPs) like lipopolysaccharide (LPS) or lipoteichoic acid (LTA) drives a proinflammatory phenotype and induces a metabolic reprogramming to sustain the cell’s function. Nevertheless, the relationship between metabolic shifts and gene...

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Detalles Bibliográficos
Autores principales: Santarsiero, Anna, Convertini, Paolo, Todisco, Simona, Pierri, Ciro L., De Grassi, Anna, Williams, Niamh C., Iacobazzi, Dominga, De Stefano, Giulio, O’Neill, Luke A. J., Infantino, Vittoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616537/
https://www.ncbi.nlm.nih.gov/pubmed/34831186
http://dx.doi.org/10.3390/cells10112962