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Downregulation of Rap1GAP Expression Activates the TGF-β/Smad3 Pathway to Inhibit the Expression of Sodium/Iodine Transporter in Papillary Thyroid Carcinoma Cells

OBJECTIVE: Rap1GAP is considered a tumor suppressor gene, but its regulatory mechanism in papillary thyroid cancer (PTC) has not been clearly elucidated. The aim of this study was to explore whether the regulation between Rap1GAP and sodium/iodine transporter (NIS) in tumorigenesis of PTC is mediate...

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Detalles Bibliográficos
Autores principales:	Yan, Zheng, Yangyanqiu, Wang, Shuwen, Han, Jing, Mao, Haihong, Liao, Gong, Chen, Yin, Jin, Qing, Zhou, Weili, Gao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616680/ https://www.ncbi.nlm.nih.gov/pubmed/34840979 http://dx.doi.org/10.1155/2021/6840642

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