IER2-induced senescence drives melanoma invasion through osteopontin

Expression of the immediate-early response gene IER2 has been associated with the progression of several types of cancer, but its functional role is poorly understood. We found that increased IER2 expression in human melanoma is associated with shorter overall survival, and subsequently investigated...

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Detalles Bibliográficos
Autores principales: Kyjacova, Lenka, Saup, Rafael, Rönsch, Kerstin, Wallbaum, Sabine, Dukowic-Schulze, Stefanie, Foss, Amelia, Scherer, Sandra D., Rothley, Melanie, Neeb, Antje, Grau, Nicole, Thiele, Wilko, Thaler, Sonja, Cremers, Natascha, Sticht, Carsten, Gretz, Norbert, Garvalov, Boyan K., Utikal, Jochen, Sleeman, Jonathan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616759/
https://www.ncbi.nlm.nih.gov/pubmed/34611309
http://dx.doi.org/10.1038/s41388-021-02027-6

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