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Protein oligomer modeling guided by predicted interchain contacts in CASP14

For CASP14, we developed deep learning‐based methods for predicting homo‐oligomeric and hetero‐oligomeric contacts and used them for oligomer modeling. To build structure models, we developed an oligomer structure generation method that utilizes predicted interchain contacts to guide iterative restr...

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Detalles Bibliográficos
Autores principales: Baek, Minkyung, Anishchenko, Ivan, Park, Hahnbeom, Humphreys, Ian R., Baker, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616806/
https://www.ncbi.nlm.nih.gov/pubmed/34324224
http://dx.doi.org/10.1002/prot.26197