AGPAT2 interaction with CDP-diacylglycerol synthases promotes the flux of fatty acids through the CDP-diacylglycerol pathway

AGPATs (1-acylglycerol-3-phosphate O-acyltransferases) catalyze the acylation of lysophosphatidic acid to form phosphatidic acid (PA), a key step in the glycerol-3-phosphate pathway for the synthesis of phospholipids and triacylglycerols. AGPAT2 is the only AGPAT isoform whose loss-of-function mutat...

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Detalles Bibliográficos
Autores principales: Mak, Hoi Yin, Ouyang, Qian, Tumanov, Sergey, Xu, Jiesi, Rong, Ping, Dong, Feitong, Lam, Sin Man, Wang, Xiaowei, Lukmantara, Ivan, Du, Ximing, Gao, Mingming, Brown, Andrew J., Gong, Xin, Shui, Guanghou, Stocker, Roland, Huang, Xun, Chen, Shuai, Yang, Hongyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616899/
https://www.ncbi.nlm.nih.gov/pubmed/34824276
http://dx.doi.org/10.1038/s41467-021-27279-4

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