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The conserved single-cleavage mechanism of animal DROSHA enzymes

RNase III enzymes typically cleave both strands of double-stranded RNAs (dsRNAs). We recently discovered that a human RNase III, DROSHA, exhibits a single cleavage on the one strand of primary microRNAs (pri-miRNAs). This study revealed that DROSHAs from the other animals, including worms and flies,...

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Detalles Bibliográficos
Autores principales:	Nguyen, Thuy Linh, Nguyen, Trung Duc, Nguyen, Tuan Anh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616936/ https://www.ncbi.nlm.nih.gov/pubmed/34824450 http://dx.doi.org/10.1038/s42003-021-02860-1

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