Progress in preeclampsia: the contribution of animal models

Recent advances have been made in understanding the nature of placental dysfunction causing preeclampsia, and other hypertensive disorders of pregnancy. The contribution of animal studies in the understanding of the effects of inadequate placentation on blood pressure and other target organs will be...

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Detalles Bibliográficos
Autores principales: Chau, Katrina, Welsh, Mikala, Makris, Angela, Hennessy, Annemarie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617007/
https://www.ncbi.nlm.nih.gov/pubmed/34837033
http://dx.doi.org/10.1038/s41371-021-00637-x
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author Chau, Katrina
Welsh, Mikala
Makris, Angela
Hennessy, Annemarie
author_facet Chau, Katrina
Welsh, Mikala
Makris, Angela
Hennessy, Annemarie
author_sort Chau, Katrina
collection PubMed
description Recent advances have been made in understanding the nature of placental dysfunction causing preeclampsia, and other hypertensive disorders of pregnancy. The contribution of animal studies in the understanding of the effects of inadequate placentation on blood pressure and other target organs will be explored in this review. This will include technical aspects of animal studies in pregnancy, as well as the translation of data regarding newly discovered pathological pathways, in particular the angiogenic pathway, into targets in clinical practice.
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spelling pubmed-86170072021-11-26 Progress in preeclampsia: the contribution of animal models Chau, Katrina Welsh, Mikala Makris, Angela Hennessy, Annemarie J Hum Hypertens Review Article Recent advances have been made in understanding the nature of placental dysfunction causing preeclampsia, and other hypertensive disorders of pregnancy. The contribution of animal studies in the understanding of the effects of inadequate placentation on blood pressure and other target organs will be explored in this review. This will include technical aspects of animal studies in pregnancy, as well as the translation of data regarding newly discovered pathological pathways, in particular the angiogenic pathway, into targets in clinical practice. Nature Publishing Group UK 2021-11-26 2022 /pmc/articles/PMC8617007/ /pubmed/34837033 http://dx.doi.org/10.1038/s41371-021-00637-x Text en © Crown 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Review Article
Chau, Katrina
Welsh, Mikala
Makris, Angela
Hennessy, Annemarie
Progress in preeclampsia: the contribution of animal models
title Progress in preeclampsia: the contribution of animal models
title_full Progress in preeclampsia: the contribution of animal models
title_fullStr Progress in preeclampsia: the contribution of animal models
title_full_unstemmed Progress in preeclampsia: the contribution of animal models
title_short Progress in preeclampsia: the contribution of animal models
title_sort progress in preeclampsia: the contribution of animal models
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617007/
https://www.ncbi.nlm.nih.gov/pubmed/34837033
http://dx.doi.org/10.1038/s41371-021-00637-x
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