Functional convalescent plasma antibodies and pre-infusion titers shape the early severe COVID-19 immune response

Transfer of convalescent plasma (CP) had been proposed early during the SARS-CoV-2 pandemic as an accessible therapy, yet trial results worldwide have been mixed, potentially due to the heterogeneous nature of CP. Here we perform deep profiling of SARS-CoV-2-specific antibody titer, Fc-receptor bind...

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Detalles Bibliográficos
Autores principales: Herman, Jonathan D., Wang, Chuangqi, Loos, Carolin, Yoon, Hyunah, Rivera, Johanna, Eugenia Dieterle, M., Haslwanter, Denise, Jangra, Rohit K., Bortz, Robert H., Bar, Katharine J., Julg, Boris, Chandran, Kartik, Lauffenburger, Douglas, Pirofski, Liise-anne, Alter, Galit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617042/
https://www.ncbi.nlm.nih.gov/pubmed/34824251
http://dx.doi.org/10.1038/s41467-021-27201-y

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