C. elegans TFIIH subunit GTF-2H5/TTDA is a non-essential transcription factor indispensable for DNA repair

The 10-subunit TFIIH complex is vital to transcription and nucleotide excision repair. Hereditary mutations in its smallest subunit, TTDA/GTF2H5, cause a photosensitive form of the rare developmental disorder trichothiodystrophy. Some trichothiodystrophy features are thought to be caused by subtle t...

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Detalles Bibliográficos
Autores principales: Thijssen, Karen L., van der Woude, Melanie, Davó-Martínez, Carlota, Dekkers, Dick H. W., Sabatella, Mariangela, Demmers, Jeroen A. A., Vermeulen, Wim, Lans, Hannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617094/
https://www.ncbi.nlm.nih.gov/pubmed/34824371
http://dx.doi.org/10.1038/s42003-021-02875-8

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