Epigenetic interaction between UTX and DNMT1 regulates diet-induced myogenic remodeling in brown fat

Brown adipocytes share the same developmental origin with skeletal muscle. Here we find that a brown adipocyte-to-myocyte remodeling also exists in mature brown adipocytes, and is induced by prolonged high fat diet (HFD) feeding, leading to brown fat dysfunction. This process is regulated by the int...

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Detalles Bibliográficos
Autores principales: Li, Fenfen, Jing, Jia, Movahed, Miranda, Cui, Xin, Cao, Qiang, Wu, Rui, Chen, Ziyue, Yu, Liqing, Pan, Yi, Shi, Huidong, Shi, Hang, Xue, Bingzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617140/
https://www.ncbi.nlm.nih.gov/pubmed/34824202
http://dx.doi.org/10.1038/s41467-021-27141-7

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