Phosphorothioate-DNA bacterial diet reduces the ROS levels in C. elegans while improving locomotion and longevity

DNA phosphorothioation (PT) is widely distributed in the human gut microbiome. In this work, PT-diet effect on nematodes was studied with PT-bioengineering bacteria. We found that the ROS level decreased by about 20–50% and the age-related lipofuscin accumulation was reduced by 15–25%. Moreover, the...

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Detalles Bibliográficos
Autores principales: Huang, Qiang, Li, Ruohan, Yi, Tao, Cong, Fengsong, Wang, Dayong, Deng, Zixin, Zhao, Yi-Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617147/
https://www.ncbi.nlm.nih.gov/pubmed/34824369
http://dx.doi.org/10.1038/s42003-021-02863-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617147/
https://www.ncbi.nlm.nih.gov/pubmed/34824369
http://dx.doi.org/10.1038/s42003-021-02863-y

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