Role of RIPK1 in SMAC mimetics-induced apoptosis in primary human HIV-infected macrophages

Macrophages serve as viral reservoirs due to their resistance to apoptosis and HIV-cytopathic effects. We have previously shown that inhibitor of apoptosis proteins (IAPs) confer resistance to HIV-Vpr-induced apoptosis in normal macrophages. Herein, we show that second mitochondrial activator of cas...

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Detalles Bibliográficos
Autores principales: Caballero, Ramon Edwin, Dong, Simon Xin Min, Gajanayaka, Niranjala, Ali, Hamza, Cassol, Edana, Cameron, William D., Korneluk, Robert, Tremblay, Michel J., Angel, Jonathan B., Kumar, Ashok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617210/
https://www.ncbi.nlm.nih.gov/pubmed/34824340
http://dx.doi.org/10.1038/s41598-021-02146-w

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