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A benchmark study of simulation methods for single-cell RNA sequencing data

Single-cell RNA-seq (scRNA-seq) data simulation is critical for evaluating computational methods for analysing scRNA-seq data especially when ground truth is experimentally unattainable. The reliability of evaluation depends on the ability of simulation methods to capture properties of experimental...

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Detalles Bibliográficos
Autores principales: Cao, Yue, Yang, Pengyi, Yang, Jean Yee Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617278/
https://www.ncbi.nlm.nih.gov/pubmed/34824223
http://dx.doi.org/10.1038/s41467-021-27130-w