Network medicine for disease module identification and drug repurposing with the NeDRex platform

Traditional drug discovery faces a severe efficacy crisis. Repurposing of registered drugs provides an alternative with lower costs and faster drug development timelines. However, the data necessary for the identification of disease modules, i.e. pathways and sub-networks describing the mechanisms o...

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Detalles Bibliográficos
Autores principales: Sadegh, Sepideh, Skelton, James, Anastasi, Elisa, Bernett, Judith, Blumenthal, David B., Galindez, Gihanna, Salgado-Albarrán, Marisol, Lazareva, Olga, Flanagan, Keith, Cockell, Simon, Nogales, Cristian, Casas, Ana I., Schmidt, Harald H. H. W., Baumbach, Jan, Wipat, Anil, Kacprowski, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617287/
https://www.ncbi.nlm.nih.gov/pubmed/34824199
http://dx.doi.org/10.1038/s41467-021-27138-2

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