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Piperine analogs arrest c-myc gene leading to downregulation of transcription for targeting cancer
G-quadruplex (G4) structures are considered a promising therapeutic target in cancer. Since Ayurveda, Piperine has been known for its medicinal properties. Piperine shows anticancer properties by stabilizing the G4 motif present upstream of the c-myc gene. This gene belongs to a group of proto-oncog...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617303/ https://www.ncbi.nlm.nih.gov/pubmed/34824301 http://dx.doi.org/10.1038/s41598-021-01529-3 |