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Elevated murine HB-EGF confers sensitivity to diphtheria toxin in EGFR-mutant lung adenocarcinoma

Conditional ablation of defined cell populations in vivo can be achieved using genetically engineered mice in which the human diphtheria toxin (DT) receptor (DTR) is placed under control of a murine tissue-specific promotor, such that delivery of DT selectively ablates cells expressing this high-aff...

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Detalles Bibliográficos
Autores principales:	Robles-Oteiza, Camila, Ayeni, Deborah, Levy, Stellar, Homer, Robert J., Kaech, Susan M., Politi, Katerina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617309/ https://www.ncbi.nlm.nih.gov/pubmed/34494649 http://dx.doi.org/10.1242/dmm.049072

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