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Acupuncture for the Treatment of Knee Osteoarthritis: An Overview of Systematic Reviews
BACKGROUND: Acupuncture has been widely used in the clinical management of osteoarthritis of the knee (KOA). Many systematic reviews (SRs) and meta-analyses (MAs) have reported its effectiveness in relieving pain. This overview aimed to summarize SRs and MAs on the effectiveness and safety of acupun...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617312/ https://www.ncbi.nlm.nih.gov/pubmed/34848997 http://dx.doi.org/10.2147/IJGM.S342435 |
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author | Chen, Jixin Liu, Aifeng Zhou, Qinxin Yu, Weijie Guo, Tianci Jia, Yizhen Yang, Kun Niu, Puyu Feng, Huichuan |
author_facet | Chen, Jixin Liu, Aifeng Zhou, Qinxin Yu, Weijie Guo, Tianci Jia, Yizhen Yang, Kun Niu, Puyu Feng, Huichuan |
author_sort | Chen, Jixin |
collection | PubMed |
description | BACKGROUND: Acupuncture has been widely used in the clinical management of osteoarthritis of the knee (KOA). Many systematic reviews (SRs) and meta-analyses (MAs) have reported its effectiveness in relieving pain. This overview aimed to summarize SRs and MAs on the effectiveness and safety of acupuncture for KOA and evaluate their methodological and evidence quality of the included SRs and MAs. METHODS: We conducted a comprehensive literature search for SRs and MAs in four Chinese and four international databases from their inception until August 2021. Two researchers independently searched the reviews, extracted the data, and cross-checked the data. The Assessing the Methodological Quality of Systematic Reviews 2 (AMSTAR 2) tool was used to evaluate the methodological quality of the included SRs and MAs. The Grades of Recommendations, Assessment, Development, and Evaluation (GRADE) system was used to assess the quality of evidence for the outcomes of the included SRs and MAs. RESULTS: A total of 14 SRs and MAs were included. The evaluation results of the AMSTAR 2 tool showed that the methodological quality of all the 14 SRs and MAs was critically low. The principal causes are the lack of a pre-registration proposal and a list of excluded studies and justify the exclusions, the report on the sources of funding, and the reasons for the study designs for inclusion. The results of the GRADE evaluation showed 25 of 46 outcomes were very low-level evidence. Seventeen were of low level, four were of moderate level and none were of high level. Most outcomes were downgraded in quality of evidence mainly because of publication bias and imprecision. CONCLUSION: The existing evidence suggests that acupuncture seems to be an effective and safe therapy for KOA. However, the deficiencies in the methodological quality and quality of evidence of the included SRs/MAs have limited the reliability of the conclusions. Therefore, further rigorous and comprehensive studies are warranted to verify the effectiveness and safety of acupuncture in KOA. |
format | Online Article Text |
id | pubmed-8617312 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-86173122021-11-29 Acupuncture for the Treatment of Knee Osteoarthritis: An Overview of Systematic Reviews Chen, Jixin Liu, Aifeng Zhou, Qinxin Yu, Weijie Guo, Tianci Jia, Yizhen Yang, Kun Niu, Puyu Feng, Huichuan Int J Gen Med Review BACKGROUND: Acupuncture has been widely used in the clinical management of osteoarthritis of the knee (KOA). Many systematic reviews (SRs) and meta-analyses (MAs) have reported its effectiveness in relieving pain. This overview aimed to summarize SRs and MAs on the effectiveness and safety of acupuncture for KOA and evaluate their methodological and evidence quality of the included SRs and MAs. METHODS: We conducted a comprehensive literature search for SRs and MAs in four Chinese and four international databases from their inception until August 2021. Two researchers independently searched the reviews, extracted the data, and cross-checked the data. The Assessing the Methodological Quality of Systematic Reviews 2 (AMSTAR 2) tool was used to evaluate the methodological quality of the included SRs and MAs. The Grades of Recommendations, Assessment, Development, and Evaluation (GRADE) system was used to assess the quality of evidence for the outcomes of the included SRs and MAs. RESULTS: A total of 14 SRs and MAs were included. The evaluation results of the AMSTAR 2 tool showed that the methodological quality of all the 14 SRs and MAs was critically low. The principal causes are the lack of a pre-registration proposal and a list of excluded studies and justify the exclusions, the report on the sources of funding, and the reasons for the study designs for inclusion. The results of the GRADE evaluation showed 25 of 46 outcomes were very low-level evidence. Seventeen were of low level, four were of moderate level and none were of high level. Most outcomes were downgraded in quality of evidence mainly because of publication bias and imprecision. CONCLUSION: The existing evidence suggests that acupuncture seems to be an effective and safe therapy for KOA. However, the deficiencies in the methodological quality and quality of evidence of the included SRs/MAs have limited the reliability of the conclusions. Therefore, further rigorous and comprehensive studies are warranted to verify the effectiveness and safety of acupuncture in KOA. Dove 2021-11-19 /pmc/articles/PMC8617312/ /pubmed/34848997 http://dx.doi.org/10.2147/IJGM.S342435 Text en © 2021 Chen et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Review Chen, Jixin Liu, Aifeng Zhou, Qinxin Yu, Weijie Guo, Tianci Jia, Yizhen Yang, Kun Niu, Puyu Feng, Huichuan Acupuncture for the Treatment of Knee Osteoarthritis: An Overview of Systematic Reviews |
title | Acupuncture for the Treatment of Knee Osteoarthritis: An Overview of Systematic Reviews |
title_full | Acupuncture for the Treatment of Knee Osteoarthritis: An Overview of Systematic Reviews |
title_fullStr | Acupuncture for the Treatment of Knee Osteoarthritis: An Overview of Systematic Reviews |
title_full_unstemmed | Acupuncture for the Treatment of Knee Osteoarthritis: An Overview of Systematic Reviews |
title_short | Acupuncture for the Treatment of Knee Osteoarthritis: An Overview of Systematic Reviews |
title_sort | acupuncture for the treatment of knee osteoarthritis: an overview of systematic reviews |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617312/ https://www.ncbi.nlm.nih.gov/pubmed/34848997 http://dx.doi.org/10.2147/IJGM.S342435 |
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