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Altered cell and RNA isoform diversity in aging Down syndrome brains

Down syndrome (DS), trisomy of human chromosome 21 (HSA21), is characterized by lifelong cognitive impairments and the development of the neuropathological hallmarks of Alzheimer’s disease (AD). The cellular and molecular modifications responsible for these effects are not understood. Here we perfor...

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Detalles Bibliográficos
Autores principales:	Palmer, Carter R., Liu, Christine S., Romanow, William J., Lee, Ming-Hsiang, Chun, Jerold
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2021
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617492/ https://www.ncbi.nlm.nih.gov/pubmed/34795060 http://dx.doi.org/10.1073/pnas.2114326118

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