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Small Molecule Inhibitors of MERTK and FLT3 Induce Cell Cycle Arrest in Human CD8(+) T Cells

There is an increasing interest in the development of Receptor Tyrosine Kinases inhibitors (RTKIs) for cancer treatment, as dysregulation of RTK expression can govern oncogenesis. Among the newer generations of RTKIs, many target Mer Tyrosine Kinase (MERTK) and Fms related RTK 3 (FLT3). Next to bein...

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Detalles Bibliográficos
Autores principales:	Powell, Richard M., Peeters, Marlies J. W., Rahbech, Anne, Aehnlich, Pia, Seremet, Tina, thor Straten, Per
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617686/ https://www.ncbi.nlm.nih.gov/pubmed/34835225 http://dx.doi.org/10.3390/vaccines9111294

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