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Assessment of the Substance Antioxidative Profile by Hyaluronan, Cu(II) and Ascorbate

In the minireview presented here, the authors discuss the evaluation of inhibitory effect of substances in the phases of initiation and propagation of high-molar-mass hyaluronan oxidative degradation. The experimental approach should be considered as original since on using a simple experimental ass...

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Detalles Bibliográficos
Autores principales: Valachová, Katarína, Šoltés, Ladislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617742/
https://www.ncbi.nlm.nih.gov/pubmed/34834230
http://dx.doi.org/10.3390/pharmaceutics13111815
Descripción
Sumario:In the minireview presented here, the authors discuss the evaluation of inhibitory effect of substances in the phases of initiation and propagation of high-molar-mass hyaluronan oxidative degradation. The experimental approach should be considered as original since on using a simple experimental assay it is possible to prove both the so-called “preventive” and “chain-breaking” antioxidant activity of investigated water-soluble endo- or exogenous substances.