Assessment of the Substance Antioxidative Profile by Hyaluronan, Cu(II) and Ascorbate

In the minireview presented here, the authors discuss the evaluation of inhibitory effect of substances in the phases of initiation and propagation of high-molar-mass hyaluronan oxidative degradation. The experimental approach should be considered as original since on using a simple experimental ass...

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Detalles Bibliográficos
Autores principales: Valachová, Katarína, Šoltés, Ladislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617742/
https://www.ncbi.nlm.nih.gov/pubmed/34834230
http://dx.doi.org/10.3390/pharmaceutics13111815
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author Valachová, Katarína
Šoltés, Ladislav
author_facet Valachová, Katarína
Šoltés, Ladislav
author_sort Valachová, Katarína
collection PubMed
description In the minireview presented here, the authors discuss the evaluation of inhibitory effect of substances in the phases of initiation and propagation of high-molar-mass hyaluronan oxidative degradation. The experimental approach should be considered as original since on using a simple experimental assay it is possible to prove both the so-called “preventive” and “chain-breaking” antioxidant activity of investigated water-soluble endo- or exogenous substances.
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spelling pubmed-86177422021-11-27 Assessment of the Substance Antioxidative Profile by Hyaluronan, Cu(II) and Ascorbate Valachová, Katarína Šoltés, Ladislav Pharmaceutics Review In the minireview presented here, the authors discuss the evaluation of inhibitory effect of substances in the phases of initiation and propagation of high-molar-mass hyaluronan oxidative degradation. The experimental approach should be considered as original since on using a simple experimental assay it is possible to prove both the so-called “preventive” and “chain-breaking” antioxidant activity of investigated water-soluble endo- or exogenous substances. MDPI 2021-10-31 /pmc/articles/PMC8617742/ /pubmed/34834230 http://dx.doi.org/10.3390/pharmaceutics13111815 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Valachová, Katarína
Šoltés, Ladislav
Assessment of the Substance Antioxidative Profile by Hyaluronan, Cu(II) and Ascorbate
title Assessment of the Substance Antioxidative Profile by Hyaluronan, Cu(II) and Ascorbate
title_full Assessment of the Substance Antioxidative Profile by Hyaluronan, Cu(II) and Ascorbate
title_fullStr Assessment of the Substance Antioxidative Profile by Hyaluronan, Cu(II) and Ascorbate
title_full_unstemmed Assessment of the Substance Antioxidative Profile by Hyaluronan, Cu(II) and Ascorbate
title_short Assessment of the Substance Antioxidative Profile by Hyaluronan, Cu(II) and Ascorbate
title_sort assessment of the substance antioxidative profile by hyaluronan, cu(ii) and ascorbate
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617742/
https://www.ncbi.nlm.nih.gov/pubmed/34834230
http://dx.doi.org/10.3390/pharmaceutics13111815
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