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Non-Cell Autonomous and Epigenetic Mechanisms of Huntington’s Disease

Huntington’s disease (HD) is a rare neurodegenerative disorder caused by an expansion of CAG trinucleotide repeat located in the exon 1 of Huntingtin (HTT) gene in human chromosome 4. The HTT protein is ubiquitously expressed in the brain. Specifically, mutant HTT (mHTT) protein-mediated toxicity le...

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Detalles Bibliográficos
Autores principales:	Kim, Chaebin, Yousefian-Jazi, Ali, Choi, Seung-Hye, Chang, Inyoung, Lee, Junghee, Ryu, Hoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617801/ https://www.ncbi.nlm.nih.gov/pubmed/34830381 http://dx.doi.org/10.3390/ijms222212499

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