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Mucoadhesive, Thermoreversible Hydrogel, Containing Tetracaine-Loaded Nanostructured Lipid Carriers for Topical, Intranasal Needle-Free Anesthesia

Recent advances have been reported for needle-free local anesthesia in maxillary teeth by administering a nasal spray of tetracaine (TTC) and oxymetazoline, without causing pain, fear, and stress. This work aimed to assess whether a TTC-loaded hybrid system could reduce cytotoxicity, promote sustain...

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Detalles Bibliográficos
Autores principales:	Calixto, Giovana Maria Fioramonti, Muniz, Bruno Vilela, Castro, Simone R., de Araujo, Jaiza Samara Macena, de Souza Amorim, Klinger, Ribeiro, Lígia N. M., Ferreira, Luiz Eduardo Nunes, de Araújo, Daniele Ribeiro, de Paula, Eneida, Franz-Montan, Michelle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617820/ https://www.ncbi.nlm.nih.gov/pubmed/34834175 http://dx.doi.org/10.3390/pharmaceutics13111760

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