An Established Th2-Oriented Response to an Alum-Adjuvanted SARS-CoV-2 Subunit Vaccine Is Not Reversible by Sequential Immunization with Nucleic Acid-Adjuvanted Th1-Oriented Subunit Vaccines

A recently reported parallel preclinical study between a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNA vaccine and an inactivated SARS-CoV-2 vaccine adjuvanted with alum showed pulmonary immunopathology typical of eosinophil accumulation in a mouse pneumonia model for the latter,...

Descripción completa

Detalles Bibliográficos
Autores principales: Cao, Han, Yang, Shengran, Wang, Yunfei, Luan, Ning, Yin, Xingxiao, Lin, Kangyang, Liu, Cunbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617830/
https://www.ncbi.nlm.nih.gov/pubmed/34835192
http://dx.doi.org/10.3390/vaccines9111261

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617830/
https://www.ncbi.nlm.nih.gov/pubmed/34835192
http://dx.doi.org/10.3390/vaccines9111261

Ejemplares similares