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Improved Deep Convolutional Neural Network to Classify Osteoarthritis from Anterior Cruciate Ligament Tear Using Magnetic Resonance Imaging

Anterior cruciate ligament (ACL) tear is caused by partially or completely torn ACL ligament in the knee, especially in sportsmen. There is a need to classify the ACL tear before it fully ruptures to avoid osteoarthritis. This research aims to identify ACL tears automatically and efficiently with a...

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Autores principales: Awan, Mazhar Javed, Rahim, Mohd Shafry Mohd, Salim, Naomie, Rehman, Amjad, Nobanee, Haitham, Shabir, Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617867/
https://www.ncbi.nlm.nih.gov/pubmed/34834515
http://dx.doi.org/10.3390/jpm11111163
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author Awan, Mazhar Javed
Rahim, Mohd Shafry Mohd
Salim, Naomie
Rehman, Amjad
Nobanee, Haitham
Shabir, Hassan
author_facet Awan, Mazhar Javed
Rahim, Mohd Shafry Mohd
Salim, Naomie
Rehman, Amjad
Nobanee, Haitham
Shabir, Hassan
author_sort Awan, Mazhar Javed
collection PubMed
description Anterior cruciate ligament (ACL) tear is caused by partially or completely torn ACL ligament in the knee, especially in sportsmen. There is a need to classify the ACL tear before it fully ruptures to avoid osteoarthritis. This research aims to identify ACL tears automatically and efficiently with a deep learning approach. A dataset was gathered, consisting of 917 knee magnetic resonance images (MRI) from Clinical Hospital Centre Rijeka, Croatia. The dataset we used consists of three classes: non-injured, partial tears, and fully ruptured knee MRI. The study compares and evaluates two variants of convolutional neural networks (CNN). We first tested the standard CNN model of five layers and then a customized CNN model of eleven layers. Eight different hyper-parameters were adjusted and tested on both variants. Our customized CNN model showed good results after a 25% random split using RMSprop and a learning rate of 0.001. The average evaluations are measured by accuracy, precision, sensitivity, specificity, and F1-score in the case of the standard CNN using the Adam optimizer with a learning rate of 0.001, i.e., 96.3%, 95%, 96%, 96.9%, and 95.6%, respectively. In the case of the customized CNN model, using the same evaluation measures, the model performed at 98.6%, 98%, 98%, 98.5%, and 98%, respectively, using an RMSprop optimizer with a learning rate of 0.001. Moreover, we also present our results on the receiver operating curve and area under the curve (ROC AUC). The customized CNN model with the Adam optimizer and a learning rate of 0.001 achieved 0.99 over three classes was highest among all. The model showed good results overall, and in the future, we can improve it to apply other CNN architectures to detect and segment other ligament parts like meniscus and cartilages.
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spelling pubmed-86178672021-11-27 Improved Deep Convolutional Neural Network to Classify Osteoarthritis from Anterior Cruciate Ligament Tear Using Magnetic Resonance Imaging Awan, Mazhar Javed Rahim, Mohd Shafry Mohd Salim, Naomie Rehman, Amjad Nobanee, Haitham Shabir, Hassan J Pers Med Article Anterior cruciate ligament (ACL) tear is caused by partially or completely torn ACL ligament in the knee, especially in sportsmen. There is a need to classify the ACL tear before it fully ruptures to avoid osteoarthritis. This research aims to identify ACL tears automatically and efficiently with a deep learning approach. A dataset was gathered, consisting of 917 knee magnetic resonance images (MRI) from Clinical Hospital Centre Rijeka, Croatia. The dataset we used consists of three classes: non-injured, partial tears, and fully ruptured knee MRI. The study compares and evaluates two variants of convolutional neural networks (CNN). We first tested the standard CNN model of five layers and then a customized CNN model of eleven layers. Eight different hyper-parameters were adjusted and tested on both variants. Our customized CNN model showed good results after a 25% random split using RMSprop and a learning rate of 0.001. The average evaluations are measured by accuracy, precision, sensitivity, specificity, and F1-score in the case of the standard CNN using the Adam optimizer with a learning rate of 0.001, i.e., 96.3%, 95%, 96%, 96.9%, and 95.6%, respectively. In the case of the customized CNN model, using the same evaluation measures, the model performed at 98.6%, 98%, 98%, 98.5%, and 98%, respectively, using an RMSprop optimizer with a learning rate of 0.001. Moreover, we also present our results on the receiver operating curve and area under the curve (ROC AUC). The customized CNN model with the Adam optimizer and a learning rate of 0.001 achieved 0.99 over three classes was highest among all. The model showed good results overall, and in the future, we can improve it to apply other CNN architectures to detect and segment other ligament parts like meniscus and cartilages. MDPI 2021-11-09 /pmc/articles/PMC8617867/ /pubmed/34834515 http://dx.doi.org/10.3390/jpm11111163 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Awan, Mazhar Javed
Rahim, Mohd Shafry Mohd
Salim, Naomie
Rehman, Amjad
Nobanee, Haitham
Shabir, Hassan
Improved Deep Convolutional Neural Network to Classify Osteoarthritis from Anterior Cruciate Ligament Tear Using Magnetic Resonance Imaging
title Improved Deep Convolutional Neural Network to Classify Osteoarthritis from Anterior Cruciate Ligament Tear Using Magnetic Resonance Imaging
title_full Improved Deep Convolutional Neural Network to Classify Osteoarthritis from Anterior Cruciate Ligament Tear Using Magnetic Resonance Imaging
title_fullStr Improved Deep Convolutional Neural Network to Classify Osteoarthritis from Anterior Cruciate Ligament Tear Using Magnetic Resonance Imaging
title_full_unstemmed Improved Deep Convolutional Neural Network to Classify Osteoarthritis from Anterior Cruciate Ligament Tear Using Magnetic Resonance Imaging
title_short Improved Deep Convolutional Neural Network to Classify Osteoarthritis from Anterior Cruciate Ligament Tear Using Magnetic Resonance Imaging
title_sort improved deep convolutional neural network to classify osteoarthritis from anterior cruciate ligament tear using magnetic resonance imaging
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617867/
https://www.ncbi.nlm.nih.gov/pubmed/34834515
http://dx.doi.org/10.3390/jpm11111163
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