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The Interface between Cell Signaling Pathways and Pregnane X Receptor
Highly expressed in the enterohepatic system, pregnane X receptor (PXR, NR1I2) is a well-characterized nuclear receptor (NR) that regulates the expression of genes in the liver and intestines that encode key drug metabolizing enzymes and drug transporter proteins in mammals. The net effect of PXR ac...
Autores principales: | Rogers, Robert S., Parker, Annemarie, Vainer, Phill D., Elliott, Elijah, Sudbeck, Dakota, Parimi, Kaushal, Peddada, Venkata P., Howe, Parker G., D’Ambrosio, Nick, Ruddy, Gregory, Stackable, Kaitlin, Carney, Megan, Martin, Lauren, Osterholt, Thomas, Staudinger, Jeff L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617909/ https://www.ncbi.nlm.nih.gov/pubmed/34831484 http://dx.doi.org/10.3390/cells10113262 |
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