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Quantitative N-Glycan Profiling of Therapeutic Monoclonal Antibodies Performed by Middle-Up Level HILIC-HRMS Analysis

The identification and accurate quantitation of the various glycoforms contained in therapeutic monoclonal antibodies (mAbs) is one of the main analytical needs in the biopharmaceutical industry, and glycosylation represents a crucial critical quality attribute (CQA) that needs to be addressed. Curr...

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Detalles Bibliográficos
Autores principales:	Duivelshof, Bastiaan L., Denorme, Steffy, Sandra, Koen, Liu, Xiaoxiao, Beck, Alain, Lauber, Matthew A., Guillarme, Davy, D’Atri, Valentina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8617915/ https://www.ncbi.nlm.nih.gov/pubmed/34834160 http://dx.doi.org/10.3390/pharmaceutics13111744

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