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DNA Transfer in Forensic Science: Recent Progress towards Meeting Challenges

Understanding the factors that may impact the transfer, persistence, prevalence and recovery of DNA (DNA-TPPR), and the availability of data to assign probabilities to DNA quantities and profile types being obtained given particular scenarios and circumstances, is paramount when performing, and givi...

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Autores principales: van Oorschot, Roland A. H., Meakin, Georgina E., Kokshoorn, Bas, Goray, Mariya, Szkuta, Bianca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618004/
https://www.ncbi.nlm.nih.gov/pubmed/34828372
http://dx.doi.org/10.3390/genes12111766
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author van Oorschot, Roland A. H.
Meakin, Georgina E.
Kokshoorn, Bas
Goray, Mariya
Szkuta, Bianca
author_facet van Oorschot, Roland A. H.
Meakin, Georgina E.
Kokshoorn, Bas
Goray, Mariya
Szkuta, Bianca
author_sort van Oorschot, Roland A. H.
collection PubMed
description Understanding the factors that may impact the transfer, persistence, prevalence and recovery of DNA (DNA-TPPR), and the availability of data to assign probabilities to DNA quantities and profile types being obtained given particular scenarios and circumstances, is paramount when performing, and giving guidance on, evaluations of DNA findings given activity level propositions (activity level evaluations). In late 2018 and early 2019, three major reviews were published on aspects of DNA-TPPR, with each advocating the need for further research and other actions to support the conduct of DNA-related activity level evaluations. Here, we look at how challenges are being met, primarily by providing a synopsis of DNA-TPPR-related articles published since the conduct of these reviews and briefly exploring some of the actions taken by industry stakeholders towards addressing identified gaps. Much has been carried out in recent years, and efforts continue, to meet the challenges to continually improve the capacity of forensic experts to provide the guidance sought by the judiciary with respect to the transfer of DNA.
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spelling pubmed-86180042021-11-27 DNA Transfer in Forensic Science: Recent Progress towards Meeting Challenges van Oorschot, Roland A. H. Meakin, Georgina E. Kokshoorn, Bas Goray, Mariya Szkuta, Bianca Genes (Basel) Review Understanding the factors that may impact the transfer, persistence, prevalence and recovery of DNA (DNA-TPPR), and the availability of data to assign probabilities to DNA quantities and profile types being obtained given particular scenarios and circumstances, is paramount when performing, and giving guidance on, evaluations of DNA findings given activity level propositions (activity level evaluations). In late 2018 and early 2019, three major reviews were published on aspects of DNA-TPPR, with each advocating the need for further research and other actions to support the conduct of DNA-related activity level evaluations. Here, we look at how challenges are being met, primarily by providing a synopsis of DNA-TPPR-related articles published since the conduct of these reviews and briefly exploring some of the actions taken by industry stakeholders towards addressing identified gaps. Much has been carried out in recent years, and efforts continue, to meet the challenges to continually improve the capacity of forensic experts to provide the guidance sought by the judiciary with respect to the transfer of DNA. MDPI 2021-11-07 /pmc/articles/PMC8618004/ /pubmed/34828372 http://dx.doi.org/10.3390/genes12111766 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
van Oorschot, Roland A. H.
Meakin, Georgina E.
Kokshoorn, Bas
Goray, Mariya
Szkuta, Bianca
DNA Transfer in Forensic Science: Recent Progress towards Meeting Challenges
title DNA Transfer in Forensic Science: Recent Progress towards Meeting Challenges
title_full DNA Transfer in Forensic Science: Recent Progress towards Meeting Challenges
title_fullStr DNA Transfer in Forensic Science: Recent Progress towards Meeting Challenges
title_full_unstemmed DNA Transfer in Forensic Science: Recent Progress towards Meeting Challenges
title_short DNA Transfer in Forensic Science: Recent Progress towards Meeting Challenges
title_sort dna transfer in forensic science: recent progress towards meeting challenges
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618004/
https://www.ncbi.nlm.nih.gov/pubmed/34828372
http://dx.doi.org/10.3390/genes12111766
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