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Immunomodulatory Nanoparticles Mitigate Macrophage Inflammation via Inhibition of PAMP Interactions and Lactate-Mediated Functional Reprogramming of NF-κB and p38 MAPK

Inflammation is a key homeostatic process involved in the body’s response to a multitude of disease states including infection, autoimmune disorders, cancer, and other chronic conditions. When the initiating event is poorly controlled, severe inflammation and globally dysregulated immune responses c...

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Detalles Bibliográficos
Autores principales: Lasola, Jackline Joy Martín, Cottingham, Andrea L., Scotland, Brianna L., Truong, Nhu, Hong, Charles C., Shapiro, Paul, Pearson, Ryan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618039/
https://www.ncbi.nlm.nih.gov/pubmed/34834256
http://dx.doi.org/10.3390/pharmaceutics13111841