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Droplet Transportation through an Orifice on Electrode for Digital Microfluidics Modulations
A digital microfluidic modular interface (chip-to-chip interface) which possesses an electrode with an orifice to vertically transport core–shell droplets is presented. The electrodes were geometrically designed to promote droplet deformation and suspension. The droplets were then applied with an el...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618053/ https://www.ncbi.nlm.nih.gov/pubmed/34832797 http://dx.doi.org/10.3390/mi12111385 |
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author | Chu, Ting-Chia Lu, Yen-Wen |
author_facet | Chu, Ting-Chia Lu, Yen-Wen |
author_sort | Chu, Ting-Chia |
collection | PubMed |
description | A digital microfluidic modular interface (chip-to-chip interface) which possesses an electrode with an orifice to vertically transport core–shell droplets is presented. The electrodes were geometrically designed to promote droplet deformation and suspension. The droplets were then applied with an electrical potential for insertion into and passage through the orifice. The concepts were tested with three types of droplets at the volume of 0.75~1.5 μL, which is usually difficult to transfer through an orifice. The integration of electrowetting on dielectric (EWOD) with paper-based microfluidics was demonstrated: the droplet could be transported within 10 s. More importantly, most of the core droplet (~97%) was extracted and passed through with only minimal shell droplets accompanying it. |
format | Online Article Text |
id | pubmed-8618053 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-86180532021-11-27 Droplet Transportation through an Orifice on Electrode for Digital Microfluidics Modulations Chu, Ting-Chia Lu, Yen-Wen Micromachines (Basel) Article A digital microfluidic modular interface (chip-to-chip interface) which possesses an electrode with an orifice to vertically transport core–shell droplets is presented. The electrodes were geometrically designed to promote droplet deformation and suspension. The droplets were then applied with an electrical potential for insertion into and passage through the orifice. The concepts were tested with three types of droplets at the volume of 0.75~1.5 μL, which is usually difficult to transfer through an orifice. The integration of electrowetting on dielectric (EWOD) with paper-based microfluidics was demonstrated: the droplet could be transported within 10 s. More importantly, most of the core droplet (~97%) was extracted and passed through with only minimal shell droplets accompanying it. MDPI 2021-11-12 /pmc/articles/PMC8618053/ /pubmed/34832797 http://dx.doi.org/10.3390/mi12111385 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Chu, Ting-Chia Lu, Yen-Wen Droplet Transportation through an Orifice on Electrode for Digital Microfluidics Modulations |
title | Droplet Transportation through an Orifice on Electrode for Digital Microfluidics Modulations |
title_full | Droplet Transportation through an Orifice on Electrode for Digital Microfluidics Modulations |
title_fullStr | Droplet Transportation through an Orifice on Electrode for Digital Microfluidics Modulations |
title_full_unstemmed | Droplet Transportation through an Orifice on Electrode for Digital Microfluidics Modulations |
title_short | Droplet Transportation through an Orifice on Electrode for Digital Microfluidics Modulations |
title_sort | droplet transportation through an orifice on electrode for digital microfluidics modulations |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618053/ https://www.ncbi.nlm.nih.gov/pubmed/34832797 http://dx.doi.org/10.3390/mi12111385 |
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