Cargando…

Droplet Transportation through an Orifice on Electrode for Digital Microfluidics Modulations

A digital microfluidic modular interface (chip-to-chip interface) which possesses an electrode with an orifice to vertically transport core–shell droplets is presented. The electrodes were geometrically designed to promote droplet deformation and suspension. The droplets were then applied with an el...

Descripción completa

Detalles Bibliográficos
Autores principales: Chu, Ting-Chia, Lu, Yen-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618053/
https://www.ncbi.nlm.nih.gov/pubmed/34832797
http://dx.doi.org/10.3390/mi12111385
_version_ 1784604655202861056
author Chu, Ting-Chia
Lu, Yen-Wen
author_facet Chu, Ting-Chia
Lu, Yen-Wen
author_sort Chu, Ting-Chia
collection PubMed
description A digital microfluidic modular interface (chip-to-chip interface) which possesses an electrode with an orifice to vertically transport core–shell droplets is presented. The electrodes were geometrically designed to promote droplet deformation and suspension. The droplets were then applied with an electrical potential for insertion into and passage through the orifice. The concepts were tested with three types of droplets at the volume of 0.75~1.5 μL, which is usually difficult to transfer through an orifice. The integration of electrowetting on dielectric (EWOD) with paper-based microfluidics was demonstrated: the droplet could be transported within 10 s. More importantly, most of the core droplet (~97%) was extracted and passed through with only minimal shell droplets accompanying it.
format Online
Article
Text
id pubmed-8618053
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-86180532021-11-27 Droplet Transportation through an Orifice on Electrode for Digital Microfluidics Modulations Chu, Ting-Chia Lu, Yen-Wen Micromachines (Basel) Article A digital microfluidic modular interface (chip-to-chip interface) which possesses an electrode with an orifice to vertically transport core–shell droplets is presented. The electrodes were geometrically designed to promote droplet deformation and suspension. The droplets were then applied with an electrical potential for insertion into and passage through the orifice. The concepts were tested with three types of droplets at the volume of 0.75~1.5 μL, which is usually difficult to transfer through an orifice. The integration of electrowetting on dielectric (EWOD) with paper-based microfluidics was demonstrated: the droplet could be transported within 10 s. More importantly, most of the core droplet (~97%) was extracted and passed through with only minimal shell droplets accompanying it. MDPI 2021-11-12 /pmc/articles/PMC8618053/ /pubmed/34832797 http://dx.doi.org/10.3390/mi12111385 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Chu, Ting-Chia
Lu, Yen-Wen
Droplet Transportation through an Orifice on Electrode for Digital Microfluidics Modulations
title Droplet Transportation through an Orifice on Electrode for Digital Microfluidics Modulations
title_full Droplet Transportation through an Orifice on Electrode for Digital Microfluidics Modulations
title_fullStr Droplet Transportation through an Orifice on Electrode for Digital Microfluidics Modulations
title_full_unstemmed Droplet Transportation through an Orifice on Electrode for Digital Microfluidics Modulations
title_short Droplet Transportation through an Orifice on Electrode for Digital Microfluidics Modulations
title_sort droplet transportation through an orifice on electrode for digital microfluidics modulations
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618053/
https://www.ncbi.nlm.nih.gov/pubmed/34832797
http://dx.doi.org/10.3390/mi12111385
work_keys_str_mv AT chutingchia droplettransportationthroughanorificeonelectrodefordigitalmicrofluidicsmodulations
AT luyenwen droplettransportationthroughanorificeonelectrodefordigitalmicrofluidicsmodulations