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The Importance of 6-Aminohexanoic Acid as a Hydrophobic, Flexible Structural Element
6-aminohexanoic acid is an ω-amino acid with a hydrophobic, flexible structure. Although the ω-amino acid in question is mainly used clinically as an antifibrinolytic drug, other applications are also interesting and important. This synthetic lysine derivative, without an α-amino group, plays a sign...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618066/ https://www.ncbi.nlm.nih.gov/pubmed/34830000 http://dx.doi.org/10.3390/ijms222212122 |
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author | Markowska, Agnieszka Markowski, Adam Roman Jarocka-Karpowicz, Iwona |
author_facet | Markowska, Agnieszka Markowski, Adam Roman Jarocka-Karpowicz, Iwona |
author_sort | Markowska, Agnieszka |
collection | PubMed |
description | 6-aminohexanoic acid is an ω-amino acid with a hydrophobic, flexible structure. Although the ω-amino acid in question is mainly used clinically as an antifibrinolytic drug, other applications are also interesting and important. This synthetic lysine derivative, without an α-amino group, plays a significant role in chemical synthesis of modified peptides and in the polyamide synthetic fibers (nylon) industry. It is also often used as a linker in various biologically active structures. This review concentrates on the role of 6-aminohexanoic acid in the structure of various molecules. |
format | Online Article Text |
id | pubmed-8618066 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-86180662021-11-27 The Importance of 6-Aminohexanoic Acid as a Hydrophobic, Flexible Structural Element Markowska, Agnieszka Markowski, Adam Roman Jarocka-Karpowicz, Iwona Int J Mol Sci Review 6-aminohexanoic acid is an ω-amino acid with a hydrophobic, flexible structure. Although the ω-amino acid in question is mainly used clinically as an antifibrinolytic drug, other applications are also interesting and important. This synthetic lysine derivative, without an α-amino group, plays a significant role in chemical synthesis of modified peptides and in the polyamide synthetic fibers (nylon) industry. It is also often used as a linker in various biologically active structures. This review concentrates on the role of 6-aminohexanoic acid in the structure of various molecules. MDPI 2021-11-09 /pmc/articles/PMC8618066/ /pubmed/34830000 http://dx.doi.org/10.3390/ijms222212122 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Markowska, Agnieszka Markowski, Adam Roman Jarocka-Karpowicz, Iwona The Importance of 6-Aminohexanoic Acid as a Hydrophobic, Flexible Structural Element |
title | The Importance of 6-Aminohexanoic Acid as a Hydrophobic, Flexible Structural Element |
title_full | The Importance of 6-Aminohexanoic Acid as a Hydrophobic, Flexible Structural Element |
title_fullStr | The Importance of 6-Aminohexanoic Acid as a Hydrophobic, Flexible Structural Element |
title_full_unstemmed | The Importance of 6-Aminohexanoic Acid as a Hydrophobic, Flexible Structural Element |
title_short | The Importance of 6-Aminohexanoic Acid as a Hydrophobic, Flexible Structural Element |
title_sort | importance of 6-aminohexanoic acid as a hydrophobic, flexible structural element |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618066/ https://www.ncbi.nlm.nih.gov/pubmed/34830000 http://dx.doi.org/10.3390/ijms222212122 |
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