Role of Endocytosis Proteins in Gefitinib-Mediated EGFR Internalisation in Glioma Cells

EGFR (epidermal growth factor receptor), a member of the ErbB tyrosine kinase receptor family, is a clinical therapeutic target in numerous solid tumours. EGFR overexpression in glioblastoma (GBM) drives cell invasion and tumour progression. However, clinical trials were disappointing, and a molecul...

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Detalles Bibliográficos
Autores principales: Cruz Da Silva, Elisabete, Choulier, Laurence, Thevenard-Devy, Jessica, Schneider, Christophe, Carl, Philippe, Rondé, Philippe, Dedieu, Stéphane, Lehmann, Maxime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618144/
https://www.ncbi.nlm.nih.gov/pubmed/34831480
http://dx.doi.org/10.3390/cells10113258

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618144/
https://www.ncbi.nlm.nih.gov/pubmed/34831480
http://dx.doi.org/10.3390/cells10113258

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