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Role of Endocytosis Proteins in Gefitinib-Mediated EGFR Internalisation in Glioma Cells

EGFR (epidermal growth factor receptor), a member of the ErbB tyrosine kinase receptor family, is a clinical therapeutic target in numerous solid tumours. EGFR overexpression in glioblastoma (GBM) drives cell invasion and tumour progression. However, clinical trials were disappointing, and a molecul...

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Detalles Bibliográficos
Autores principales:	Cruz Da Silva, Elisabete, Choulier, Laurence, Thevenard-Devy, Jessica, Schneider, Christophe, Carl, Philippe, Rondé, Philippe, Dedieu, Stéphane, Lehmann, Maxime
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618144/ https://www.ncbi.nlm.nih.gov/pubmed/34831480 http://dx.doi.org/10.3390/cells10113258

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