Transcriptome Analysis of Insulin Signaling-Associated Transcription Factors in C. elegans Reveal Their Genome-Wide Target Genes Specificity and Complexity

Insulin/IGF-1-like signaling (IIS) plays a crucial, conserved role in development, growth, reproduction, stress tolerance, and longevity. In Caenorhabditis elegans, the enhanced longevity under reduced insulin signaling (rIIS) is primarily regulated by the transcription factors (TFs) DAF-16/FOXO, SK...

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Detalles Bibliográficos
Autores principales: Kaushik, Neha, Rastogi, Soumya, Verma, Sonia, Pandey, Deepak, Halder, Ashutosh, Mukhopadhyay, Arnab, Kumar, Neeraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618238/
https://www.ncbi.nlm.nih.gov/pubmed/34830338
http://dx.doi.org/10.3390/ijms222212462

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