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Current Status of Photodynamic Diagnosis for Gastric Tumors
Although the recent development and widespread use of image-enhanced endoscopy and magnifying endoscopy have improved endoscopic diagnosis of gastric cancer, it is somewhat complicated, requires a higher level of expertise, and is still subjective. Photodynamic endoscopic diagnosis (PDED) is based o...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618298/ https://www.ncbi.nlm.nih.gov/pubmed/34829314 http://dx.doi.org/10.3390/diagnostics11111967 |
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author | Kurumi, Hiroki Kanda, Tsutomu Ikebuchi, Yuichiro Yoshida, Akira Kawaguchi, Koichiro Yashima, Kazuo Isomoto, Hajime |
author_facet | Kurumi, Hiroki Kanda, Tsutomu Ikebuchi, Yuichiro Yoshida, Akira Kawaguchi, Koichiro Yashima, Kazuo Isomoto, Hajime |
author_sort | Kurumi, Hiroki |
collection | PubMed |
description | Although the recent development and widespread use of image-enhanced endoscopy and magnifying endoscopy have improved endoscopic diagnosis of gastric cancer, it is somewhat complicated, requires a higher level of expertise, and is still subjective. Photodynamic endoscopic diagnosis (PDED) is based on the fluorescence of photosensitizers that accumulate in tumors, which enables objective evaluation independent of the endoscopist’s experience, and is useful for tumor detection. The objective of this work was to perform a narrative review of PDED for gastric tumors and to introduce our approach to PDED in gastric tumors in our hospital. In our review there have been case reports of PDED for gastric cancer, but its usefulness has not been established because no prospective studies evaluating its usefulness have been performed. In our previous study, 85.7% (42/49) of gastric tumors exhibited fluorescence in PDED. PDED may be useful in the diagnosis of early gastric cancer. Our previous studies were pilot studies in cancer patients; therefore, future prospective studies are required to verify the usefulness of PDED. |
format | Online Article Text |
id | pubmed-8618298 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-86182982021-11-27 Current Status of Photodynamic Diagnosis for Gastric Tumors Kurumi, Hiroki Kanda, Tsutomu Ikebuchi, Yuichiro Yoshida, Akira Kawaguchi, Koichiro Yashima, Kazuo Isomoto, Hajime Diagnostics (Basel) Review Although the recent development and widespread use of image-enhanced endoscopy and magnifying endoscopy have improved endoscopic diagnosis of gastric cancer, it is somewhat complicated, requires a higher level of expertise, and is still subjective. Photodynamic endoscopic diagnosis (PDED) is based on the fluorescence of photosensitizers that accumulate in tumors, which enables objective evaluation independent of the endoscopist’s experience, and is useful for tumor detection. The objective of this work was to perform a narrative review of PDED for gastric tumors and to introduce our approach to PDED in gastric tumors in our hospital. In our review there have been case reports of PDED for gastric cancer, but its usefulness has not been established because no prospective studies evaluating its usefulness have been performed. In our previous study, 85.7% (42/49) of gastric tumors exhibited fluorescence in PDED. PDED may be useful in the diagnosis of early gastric cancer. Our previous studies were pilot studies in cancer patients; therefore, future prospective studies are required to verify the usefulness of PDED. MDPI 2021-10-22 /pmc/articles/PMC8618298/ /pubmed/34829314 http://dx.doi.org/10.3390/diagnostics11111967 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Kurumi, Hiroki Kanda, Tsutomu Ikebuchi, Yuichiro Yoshida, Akira Kawaguchi, Koichiro Yashima, Kazuo Isomoto, Hajime Current Status of Photodynamic Diagnosis for Gastric Tumors |
title | Current Status of Photodynamic Diagnosis for Gastric Tumors |
title_full | Current Status of Photodynamic Diagnosis for Gastric Tumors |
title_fullStr | Current Status of Photodynamic Diagnosis for Gastric Tumors |
title_full_unstemmed | Current Status of Photodynamic Diagnosis for Gastric Tumors |
title_short | Current Status of Photodynamic Diagnosis for Gastric Tumors |
title_sort | current status of photodynamic diagnosis for gastric tumors |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618298/ https://www.ncbi.nlm.nih.gov/pubmed/34829314 http://dx.doi.org/10.3390/diagnostics11111967 |
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