Cargando…

IFN-Gamma and TNF-Alpha as a Priming Strategy to Enhance the Immunomodulatory Capacity of Secretomes from Menstrual Blood-Derived Stromal Cells

Mesenchymal stromal cells isolated from menstrual blood (MenSCs) exhibit a potent pro-angiogenic and immunomodulatory capacity. Their therapeutic effect is mediated by paracrine mediators released by their secretomes. In this work, we aimed to evaluate the effect of a specific priming condition on t...

Descripción completa

Detalles Bibliográficos
Autores principales:	de Pedro, María Ángeles, Gómez-Serrano, María, Marinaro, Federica, López, Esther, Pulido, María, Preußer, Christian, Pogge von Strandmann, Elke, Sánchez-Margallo, Francisco Miguel, Álvarez, Verónica, Casado, Javier G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618369/ https://www.ncbi.nlm.nih.gov/pubmed/34830067 http://dx.doi.org/10.3390/ijms222212177

Ejemplares similares

Menstrual blood-derived stromal cells: insights into their secretome in acute hypoxia conditions
por: de Pedro, María Ángeles, et al.
Publicado: (2023)

Menstrual blood-derived mesenchymal stromal cells: impact of preconditioning on the cargo of extracellular vesicles as potential therapeutics
por: de Pedro, María Ángeles, et al.
Publicado: (2023)

The Immunomodulatory Signature of Extracellular Vesicles From Cardiosphere-Derived Cells: A Proteomic and miRNA Profiling
por: López, Esther, et al.
Publicado: (2020)

Intrapericardial Administration of Secretomes from Menstrual Blood-Derived Mesenchymal Stromal Cells: Effects on Immune-Related Genes in a Porcine Model of Myocardial Infarction
por: de Pedro, María Ángeles, et al.
Publicado: (2022)

Beyond the Extracellular Vesicles: Technical Hurdles, Achieved Goals and Current Challenges When Working on Adipose Cells
por: Gómez-Serrano, María, et al.
Publicado: (2021)

Molecular Determinants for RNA Release into Extracellular Vesicles
por: Mosbach, Marie-Luise, et al.
Publicado: (2021)

Conditioned Serum Enhances the Chondrogenic and Immunomodulatory Behavior of Mesenchymal Stem Cells
por: Blázquez, Rebeca, et al.
Publicado: (2019)

Hodgkin Lymphoma-Derived Extracellular Vesicles Change the Secretome of Fibroblasts Toward a CAF Phenotype
por: Dörsam, Bastian, et al.
Publicado: (2018)

A Fibrin Coating Method of Polypropylene Meshes Enables the Adhesion of Menstrual Blood-Derived Mesenchymal Stromal Cells: A New Delivery Strategy for Stem Cell-Based Therapies
por: Marinaro, Federica, et al.
Publicado: (2021)

Late domain dependent E-cadherin recruitment into extracellular vesicles
por: Bänfer, Sebastian, et al.
Publicado: (2022)

The Role of Extracellular HSP70 in the Function of Tumor-Associated Immune Cells
por: Linder, Manuel, et al.
Publicado: (2021)

Secreted Ligands of the NK Cell Receptor NKp30: B7-H6 Is in Contrast to BAG6 Only Marginally Released via Extracellular Vesicles
por: Ponath, Viviane, et al.
Publicado: (2021)

Role of TNF-Alpha, IFN-Gamma, and IL-10 in the Development of Pulmonary Tuberculosis
por: Cavalcanti, Yone Vila Nova, et al.
Publicado: (2012)

Cancer-derived extracellular vesicles: friend and foe of tumour immunosurveillance
por: Dörsam, Bastian, et al.
Publicado: (2018)

Antigen Loss Variants: Catching Hold of Escaping Foes
por: Vyas, Maulik, et al.
Publicado: (2017)

Exploring the immunomodulatory role of virtual memory CD8(+) T cells: Role of IFN gamma in tumor growth control
por: Savid-Frontera, Constanza, et al.
Publicado: (2022)

Role of Exosomes Released by Dendritic Cells and/or by Tumor Targets: Regulation of NK Cell Plasticity
por: Reiners, Katrin S., et al.
Publicado: (2014)

IFN-gamma and TNF associated with severe falciparum malaria infection in Saudi pregnant women
por: Nasr, Amre, et al.
Publicado: (2014)

Levels of Salivary IFN-gamma, TNF-Alfa, and TNF Receptor-2 As Prognostic Markers in (Erosive) Oral Lichen Planus
por: Ghallab, Noha A., et al.
Publicado: (2010)

Interleukin 12 induces stable priming for interferon gamma (IFN-gamma) production during differentiation of human T helper (Th) cells and transient IFN-gamma production in established Th2 cell clones
Publicado: (1994)

Interferon (IFN)-λ Takes the Helm: Immunomodulatory Roles of Type III IFNs
por: Zanoni, Ivan, et al.
Publicado: (2017)

Bacterial extracellular vesicles repress the vascular protective factor RNase1 in human lung endothelial cells
por: Laakmann, Katrin, et al.
Publicado: (2023)

Epigenetic Regulation of Airway Epithelium Immune Functions in Asthma
por: Alashkar Alhamwe, Bilal, et al.
Publicado: (2020)

Phosphoproteomics identify arachidonic-acid-regulated signal transduction pathways modulating macrophage functions with implications for ovarian cancer
por: Dietze, Raimund, et al.
Publicado: (2021)

The Neutrophil Secretome as a Crucial Link between Inflammation and Thrombosis
por: Blanch-Ruiz, María Amparo, et al.
Publicado: (2021)

Effect of Comedications and Endotoxins on Mesenchymal Stem Cell Secretomes, Migratory and Immunomodulatory Capacity
por: Durand, Nisha, et al.
Publicado: (2019)

Inflammation Alters the Secretome and Immunomodulatory Properties of Human Skin-Derived Precursor Cells
por: De Kock, Joery, et al.
Publicado: (2020)

Side-Directed Release of Differential Extracellular Vesicle-associated microRNA Profiles from Bronchial Epithelial Cells of Healthy and Asthmatic Subjects
por: Schindler, Viktoria E. M., et al.
Publicado: (2022)

TNF-α Priming Elicits Robust Immunomodulatory Potential of Human Tonsil-Derived Mesenchymal Stem Cells to Alleviate Murine Colitis
por: Shin, Tae-Hoon, et al.
Publicado: (2020)

TNF/IFN-GAMMA AXIS FAVORS SENESCENCE AND SEVERE INFLAMMATION ASSOCIATED WITH CELL DEATH IN PATIENTS WITH COVID-19
por: PALACIOS, Y., et al.
Publicado: (2022)

ADAM8-Dependent Extracellular Signaling in the Tumor Microenvironment Involves Regulated Release of Lipocalin 2 and MMP-9
por: Cook, Lena, et al.
Publicado: (2022)

Murine embryos exposed to human endometrial MSCs-derived extracellular vesicles exhibit higher VEGF/PDGF AA release, increased blastomere count and hatching rates
por: Blázquez, Rebeca, et al.
Publicado: (2018)

Mesenchymal Stem Cell-Derived Exosomes: Immunomodulatory Evaluation in an Antigen-Induced Synovitis Porcine Model
por: Casado, Javier G., et al.
Publicado: (2017)

DNA damage response and evasion from immunosurveillance in CLL: new options for NK cell-based immunotherapies
por: Shatnyeva, Olga M., et al.
Publicado: (2015)

The Unique Molecular and Cellular Microenvironment of Ovarian Cancer
por: Worzfeld, Thomas, et al.
Publicado: (2017)

KLF4-mediated upregulation of the NKG2D ligand MICA in acute myeloid leukemia: a novel therapeutic target identified by enChIP
por: Alkhayer, Reem, et al.
Publicado: (2023)

Unraveling the Molecular Signature of Extracellular Vesicles From Endometrial-Derived Mesenchymal Stem Cells: Potential Modulatory Effects and Therapeutic Applications
por: Marinaro, Federica, et al.
Publicado: (2019)

TNF-α Regulated Endometrial Stroma Secretome Promotes Trophoblast Invasion
por: You, Yuan, et al.
Publicado: (2021)

Mitochondrial CMPK2 mediates immunomodulatory and antiviral activities through IFN-dependent and IFN-independent pathways
por: Lai, Jenn-Haung, et al.
Publicado: (2021)

High IFN-gamma and TNF production by peripheral NK cells of Colombian patients with different clinical presentation of Plasmodium falciparum
por: Agudelo, Olga, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_hb8kail081hm8vgrpvinl8dqei