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Laser Ablation Treatment of Recurrent Lymph Node Metastases from Papillary Thyroid Carcinoma
(1) Background: The incidence of papillary thyroid cancers is increasing. Papillary neoplasm metastasizes to the central and lateral lymph nodes of the neck. The recurrence rate is less than 30%. The gold standard of treatment for lymph node recurrences is surgery, but surgery is burdened by a high...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618398/ https://www.ncbi.nlm.nih.gov/pubmed/34830577 http://dx.doi.org/10.3390/jcm10225295 |
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author | Offi, Chiara Misso, Claudia Antonelli, Giovanni Esposito, Maria Grazia Brancaccio, Umberto Spiezia, Stefano |
author_facet | Offi, Chiara Misso, Claudia Antonelli, Giovanni Esposito, Maria Grazia Brancaccio, Umberto Spiezia, Stefano |
author_sort | Offi, Chiara |
collection | PubMed |
description | (1) Background: The incidence of papillary thyroid cancers is increasing. Papillary neoplasm metastasizes to the central and lateral lymph nodes of the neck. The recurrence rate is less than 30%. The gold standard of treatment for lymph node recurrences is surgery, but surgery is burdened by a high rate of complications. Therefore, laser ablation of recurrent lymph nodes has been recognized as an alternative treatment with minimal invasiveness, a low complication rate and a curative effect. (2) Methods: We analyzed 10 patients who underwent a total thyroidectomy and metabolic radiotherapy and who developed a lymph node recurrence in the laterocervical compartment in the following 12–18 months. (3) Results: Patients developed lymph node recurrence at IV and Vb levels in 70% and 30% of cases, respectively. All patients were treated with a single laser ablative session. Hydrodissection was performed in all patients. The energy delivered was 1120 ± 159.3 Joules and 3–4 Watts in 362 ± 45.7 s. No complications were reported. All patients underwent a 6-month follow-up. A volumetric reduction of 40.12 ± 2.2%, 49.1 ± 2.13% and 59.8 ± 3.05%, respectively at 1-, 3- and 6-months of follow-up was reported. (4) Conclusions: At 6 months, a fine needle aspiration was performed, which was negative for malignant cells and negative for a dosage of Thyroglobulin in eluate. The laser ablation is an effective alternative to surgical treatment. |
format | Online Article Text |
id | pubmed-8618398 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-86183982021-11-27 Laser Ablation Treatment of Recurrent Lymph Node Metastases from Papillary Thyroid Carcinoma Offi, Chiara Misso, Claudia Antonelli, Giovanni Esposito, Maria Grazia Brancaccio, Umberto Spiezia, Stefano J Clin Med Article (1) Background: The incidence of papillary thyroid cancers is increasing. Papillary neoplasm metastasizes to the central and lateral lymph nodes of the neck. The recurrence rate is less than 30%. The gold standard of treatment for lymph node recurrences is surgery, but surgery is burdened by a high rate of complications. Therefore, laser ablation of recurrent lymph nodes has been recognized as an alternative treatment with minimal invasiveness, a low complication rate and a curative effect. (2) Methods: We analyzed 10 patients who underwent a total thyroidectomy and metabolic radiotherapy and who developed a lymph node recurrence in the laterocervical compartment in the following 12–18 months. (3) Results: Patients developed lymph node recurrence at IV and Vb levels in 70% and 30% of cases, respectively. All patients were treated with a single laser ablative session. Hydrodissection was performed in all patients. The energy delivered was 1120 ± 159.3 Joules and 3–4 Watts in 362 ± 45.7 s. No complications were reported. All patients underwent a 6-month follow-up. A volumetric reduction of 40.12 ± 2.2%, 49.1 ± 2.13% and 59.8 ± 3.05%, respectively at 1-, 3- and 6-months of follow-up was reported. (4) Conclusions: At 6 months, a fine needle aspiration was performed, which was negative for malignant cells and negative for a dosage of Thyroglobulin in eluate. The laser ablation is an effective alternative to surgical treatment. MDPI 2021-11-14 /pmc/articles/PMC8618398/ /pubmed/34830577 http://dx.doi.org/10.3390/jcm10225295 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Offi, Chiara Misso, Claudia Antonelli, Giovanni Esposito, Maria Grazia Brancaccio, Umberto Spiezia, Stefano Laser Ablation Treatment of Recurrent Lymph Node Metastases from Papillary Thyroid Carcinoma |
title | Laser Ablation Treatment of Recurrent Lymph Node Metastases from Papillary Thyroid Carcinoma |
title_full | Laser Ablation Treatment of Recurrent Lymph Node Metastases from Papillary Thyroid Carcinoma |
title_fullStr | Laser Ablation Treatment of Recurrent Lymph Node Metastases from Papillary Thyroid Carcinoma |
title_full_unstemmed | Laser Ablation Treatment of Recurrent Lymph Node Metastases from Papillary Thyroid Carcinoma |
title_short | Laser Ablation Treatment of Recurrent Lymph Node Metastases from Papillary Thyroid Carcinoma |
title_sort | laser ablation treatment of recurrent lymph node metastases from papillary thyroid carcinoma |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618398/ https://www.ncbi.nlm.nih.gov/pubmed/34830577 http://dx.doi.org/10.3390/jcm10225295 |
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