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COVID-19 ARDS: Points to Be Considered in Mechanical Ventilation and Weaning

The COVID-19 disease can cause hypoxemic respiratory failure due to ARDS, requiring invasive mechanical ventilation. Although early studies reported that COVID-19-associated ARDS has distinctive features from ARDS of other causes, recent observational studies have demonstrated that ARDS related to C...

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Autores principales: Kondili, Eumorfia, Makris, Demosthenes, Georgopoulos, Dimitrios, Rovina, Nikoletta, Kotanidou, Anastasia, Koutsoukou, Antonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618434/
https://www.ncbi.nlm.nih.gov/pubmed/34834461
http://dx.doi.org/10.3390/jpm11111109
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author Kondili, Eumorfia
Makris, Demosthenes
Georgopoulos, Dimitrios
Rovina, Nikoletta
Kotanidou, Anastasia
Koutsoukou, Antonia
author_facet Kondili, Eumorfia
Makris, Demosthenes
Georgopoulos, Dimitrios
Rovina, Nikoletta
Kotanidou, Anastasia
Koutsoukou, Antonia
author_sort Kondili, Eumorfia
collection PubMed
description The COVID-19 disease can cause hypoxemic respiratory failure due to ARDS, requiring invasive mechanical ventilation. Although early studies reported that COVID-19-associated ARDS has distinctive features from ARDS of other causes, recent observational studies have demonstrated that ARDS related to COVID-19 shares common clinical characteristics and respiratory system mechanics with ARDS of other origins. Therefore, mechanical ventilation in these patients should be based on strategies aiming to mitigate ventilator-induced lung injury. Assisted mechanical ventilation should be applied early in the course of mechanical ventilation by considering evaluation and minimizing factors associated with patient-inflicted lung injury. Extracorporeal membrane oxygenation should be considered in selected patients with refractory hypoxia not responding to conventional ventilation strategies. This review highlights the current and evolving practice in managing mechanically ventilated patients with ARDS related to COVID-19.
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spelling pubmed-86184342021-11-27 COVID-19 ARDS: Points to Be Considered in Mechanical Ventilation and Weaning Kondili, Eumorfia Makris, Demosthenes Georgopoulos, Dimitrios Rovina, Nikoletta Kotanidou, Anastasia Koutsoukou, Antonia J Pers Med Review The COVID-19 disease can cause hypoxemic respiratory failure due to ARDS, requiring invasive mechanical ventilation. Although early studies reported that COVID-19-associated ARDS has distinctive features from ARDS of other causes, recent observational studies have demonstrated that ARDS related to COVID-19 shares common clinical characteristics and respiratory system mechanics with ARDS of other origins. Therefore, mechanical ventilation in these patients should be based on strategies aiming to mitigate ventilator-induced lung injury. Assisted mechanical ventilation should be applied early in the course of mechanical ventilation by considering evaluation and minimizing factors associated with patient-inflicted lung injury. Extracorporeal membrane oxygenation should be considered in selected patients with refractory hypoxia not responding to conventional ventilation strategies. This review highlights the current and evolving practice in managing mechanically ventilated patients with ARDS related to COVID-19. MDPI 2021-10-28 /pmc/articles/PMC8618434/ /pubmed/34834461 http://dx.doi.org/10.3390/jpm11111109 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Kondili, Eumorfia
Makris, Demosthenes
Georgopoulos, Dimitrios
Rovina, Nikoletta
Kotanidou, Anastasia
Koutsoukou, Antonia
COVID-19 ARDS: Points to Be Considered in Mechanical Ventilation and Weaning
title COVID-19 ARDS: Points to Be Considered in Mechanical Ventilation and Weaning
title_full COVID-19 ARDS: Points to Be Considered in Mechanical Ventilation and Weaning
title_fullStr COVID-19 ARDS: Points to Be Considered in Mechanical Ventilation and Weaning
title_full_unstemmed COVID-19 ARDS: Points to Be Considered in Mechanical Ventilation and Weaning
title_short COVID-19 ARDS: Points to Be Considered in Mechanical Ventilation and Weaning
title_sort covid-19 ards: points to be considered in mechanical ventilation and weaning
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618434/
https://www.ncbi.nlm.nih.gov/pubmed/34834461
http://dx.doi.org/10.3390/jpm11111109
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