Overexpression of Plasmodium falciparum M1 Aminopeptidase Promotes an Increase in Intracellular Proteolysis and Modifies the Asexual Erythrocytic Cycle Development

Plasmodium falciparum, the most virulent of the human malaria parasite, is responsible for high mortality rates worldwide. We studied the M1 alanyl-aminopeptidase of this protozoan (PfA-M1), which is involved in the final stages of hemoglobin cleavage, an essential process for parasite survival. Aim...

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Detalles Bibliográficos
Autores principales: Hoff, Carolina C., Azevedo, Mauro F., Thurler, Adriana B., Maluf, Sarah El Chamy, Melo, Pollyana M. S., del Rivero, Maday Alonso, González-Bacerio, Jorge, Carmona, Adriana K., Budu, Alexandre, Gazarini, Marcos L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618464/
https://www.ncbi.nlm.nih.gov/pubmed/34832608
http://dx.doi.org/10.3390/pathogens10111452

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