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Fungal Septic Knee Arthritis Caused by Aspergillus fumigatus following Anterior Cruciate Ligament Reconstruction
Postoperative infections after arthroscopic anterior cruciate ligament (ACL) reconstruction (ACLR) represent a rare but severe complication. An extremely rare case of Aspergillus septic arthritis in a 27-year-old patient following arthroscopic ACLR is reported. The patient presented with signs of kn...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618586/ https://www.ncbi.nlm.nih.gov/pubmed/34829322 http://dx.doi.org/10.3390/diagnostics11111975 |
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author | Samonis, George Koutserimpas, Christos Vrioni, Georgia Kampos Martinez, Elsa Kouloumentas, Panagiotis Alpantaki, Kalliopi Saroglou, George |
author_facet | Samonis, George Koutserimpas, Christos Vrioni, Georgia Kampos Martinez, Elsa Kouloumentas, Panagiotis Alpantaki, Kalliopi Saroglou, George |
author_sort | Samonis, George |
collection | PubMed |
description | Postoperative infections after arthroscopic anterior cruciate ligament (ACL) reconstruction (ACLR) represent a rare but severe complication. An extremely rare case of Aspergillus septic arthritis in a 27-year-old patient following arthroscopic ACLR is reported. The patient presented with signs of knee infection 14 days after ACLR. Two consecutive arthroscopic debridements were performed, while eventually histopathology, cultures and multiplex PCR test revealed Aspergillus identified as A. fumigatus by mass spectrometry. The patient commenced long-term treatment with voriconazole. Fungal arthritis or osteomyelitis following ACLR has a mild local and general inflammatory reaction when compared to the bacterial ones. Nevertheless, such infections may lead to aggressive osseous destruction and necrosis. A high index of suspicion is of utmost importance for early detection, while microscopic, histological examination and multiplex PCR may be more helpful for the diagnosis than cultures since cultures are more time-consuming and may vary depending on different factors. |
format | Online Article Text |
id | pubmed-8618586 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-86185862021-11-27 Fungal Septic Knee Arthritis Caused by Aspergillus fumigatus following Anterior Cruciate Ligament Reconstruction Samonis, George Koutserimpas, Christos Vrioni, Georgia Kampos Martinez, Elsa Kouloumentas, Panagiotis Alpantaki, Kalliopi Saroglou, George Diagnostics (Basel) Case Report Postoperative infections after arthroscopic anterior cruciate ligament (ACL) reconstruction (ACLR) represent a rare but severe complication. An extremely rare case of Aspergillus septic arthritis in a 27-year-old patient following arthroscopic ACLR is reported. The patient presented with signs of knee infection 14 days after ACLR. Two consecutive arthroscopic debridements were performed, while eventually histopathology, cultures and multiplex PCR test revealed Aspergillus identified as A. fumigatus by mass spectrometry. The patient commenced long-term treatment with voriconazole. Fungal arthritis or osteomyelitis following ACLR has a mild local and general inflammatory reaction when compared to the bacterial ones. Nevertheless, such infections may lead to aggressive osseous destruction and necrosis. A high index of suspicion is of utmost importance for early detection, while microscopic, histological examination and multiplex PCR may be more helpful for the diagnosis than cultures since cultures are more time-consuming and may vary depending on different factors. MDPI 2021-10-24 /pmc/articles/PMC8618586/ /pubmed/34829322 http://dx.doi.org/10.3390/diagnostics11111975 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Samonis, George Koutserimpas, Christos Vrioni, Georgia Kampos Martinez, Elsa Kouloumentas, Panagiotis Alpantaki, Kalliopi Saroglou, George Fungal Septic Knee Arthritis Caused by Aspergillus fumigatus following Anterior Cruciate Ligament Reconstruction |
title | Fungal Septic Knee Arthritis Caused by Aspergillus fumigatus following Anterior Cruciate Ligament Reconstruction |
title_full | Fungal Septic Knee Arthritis Caused by Aspergillus fumigatus following Anterior Cruciate Ligament Reconstruction |
title_fullStr | Fungal Septic Knee Arthritis Caused by Aspergillus fumigatus following Anterior Cruciate Ligament Reconstruction |
title_full_unstemmed | Fungal Septic Knee Arthritis Caused by Aspergillus fumigatus following Anterior Cruciate Ligament Reconstruction |
title_short | Fungal Septic Knee Arthritis Caused by Aspergillus fumigatus following Anterior Cruciate Ligament Reconstruction |
title_sort | fungal septic knee arthritis caused by aspergillus fumigatus following anterior cruciate ligament reconstruction |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618586/ https://www.ncbi.nlm.nih.gov/pubmed/34829322 http://dx.doi.org/10.3390/diagnostics11111975 |
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