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Fungal Septic Knee Arthritis Caused by Aspergillus fumigatus following Anterior Cruciate Ligament Reconstruction

Postoperative infections after arthroscopic anterior cruciate ligament (ACL) reconstruction (ACLR) represent a rare but severe complication. An extremely rare case of Aspergillus septic arthritis in a 27-year-old patient following arthroscopic ACLR is reported. The patient presented with signs of kn...

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Autores principales: Samonis, George, Koutserimpas, Christos, Vrioni, Georgia, Kampos Martinez, Elsa, Kouloumentas, Panagiotis, Alpantaki, Kalliopi, Saroglou, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618586/
https://www.ncbi.nlm.nih.gov/pubmed/34829322
http://dx.doi.org/10.3390/diagnostics11111975
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author Samonis, George
Koutserimpas, Christos
Vrioni, Georgia
Kampos Martinez, Elsa
Kouloumentas, Panagiotis
Alpantaki, Kalliopi
Saroglou, George
author_facet Samonis, George
Koutserimpas, Christos
Vrioni, Georgia
Kampos Martinez, Elsa
Kouloumentas, Panagiotis
Alpantaki, Kalliopi
Saroglou, George
author_sort Samonis, George
collection PubMed
description Postoperative infections after arthroscopic anterior cruciate ligament (ACL) reconstruction (ACLR) represent a rare but severe complication. An extremely rare case of Aspergillus septic arthritis in a 27-year-old patient following arthroscopic ACLR is reported. The patient presented with signs of knee infection 14 days after ACLR. Two consecutive arthroscopic debridements were performed, while eventually histopathology, cultures and multiplex PCR test revealed Aspergillus identified as A. fumigatus by mass spectrometry. The patient commenced long-term treatment with voriconazole. Fungal arthritis or osteomyelitis following ACLR has a mild local and general inflammatory reaction when compared to the bacterial ones. Nevertheless, such infections may lead to aggressive osseous destruction and necrosis. A high index of suspicion is of utmost importance for early detection, while microscopic, histological examination and multiplex PCR may be more helpful for the diagnosis than cultures since cultures are more time-consuming and may vary depending on different factors.
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spelling pubmed-86185862021-11-27 Fungal Septic Knee Arthritis Caused by Aspergillus fumigatus following Anterior Cruciate Ligament Reconstruction Samonis, George Koutserimpas, Christos Vrioni, Georgia Kampos Martinez, Elsa Kouloumentas, Panagiotis Alpantaki, Kalliopi Saroglou, George Diagnostics (Basel) Case Report Postoperative infections after arthroscopic anterior cruciate ligament (ACL) reconstruction (ACLR) represent a rare but severe complication. An extremely rare case of Aspergillus septic arthritis in a 27-year-old patient following arthroscopic ACLR is reported. The patient presented with signs of knee infection 14 days after ACLR. Two consecutive arthroscopic debridements were performed, while eventually histopathology, cultures and multiplex PCR test revealed Aspergillus identified as A. fumigatus by mass spectrometry. The patient commenced long-term treatment with voriconazole. Fungal arthritis or osteomyelitis following ACLR has a mild local and general inflammatory reaction when compared to the bacterial ones. Nevertheless, such infections may lead to aggressive osseous destruction and necrosis. A high index of suspicion is of utmost importance for early detection, while microscopic, histological examination and multiplex PCR may be more helpful for the diagnosis than cultures since cultures are more time-consuming and may vary depending on different factors. MDPI 2021-10-24 /pmc/articles/PMC8618586/ /pubmed/34829322 http://dx.doi.org/10.3390/diagnostics11111975 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Samonis, George
Koutserimpas, Christos
Vrioni, Georgia
Kampos Martinez, Elsa
Kouloumentas, Panagiotis
Alpantaki, Kalliopi
Saroglou, George
Fungal Septic Knee Arthritis Caused by Aspergillus fumigatus following Anterior Cruciate Ligament Reconstruction
title Fungal Septic Knee Arthritis Caused by Aspergillus fumigatus following Anterior Cruciate Ligament Reconstruction
title_full Fungal Septic Knee Arthritis Caused by Aspergillus fumigatus following Anterior Cruciate Ligament Reconstruction
title_fullStr Fungal Septic Knee Arthritis Caused by Aspergillus fumigatus following Anterior Cruciate Ligament Reconstruction
title_full_unstemmed Fungal Septic Knee Arthritis Caused by Aspergillus fumigatus following Anterior Cruciate Ligament Reconstruction
title_short Fungal Septic Knee Arthritis Caused by Aspergillus fumigatus following Anterior Cruciate Ligament Reconstruction
title_sort fungal septic knee arthritis caused by aspergillus fumigatus following anterior cruciate ligament reconstruction
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618586/
https://www.ncbi.nlm.nih.gov/pubmed/34829322
http://dx.doi.org/10.3390/diagnostics11111975
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