Cargando…

Evaluating the Functional Outcomes and the Quality of Life for Pediatric Patients with Osteogenesis Imperfecta after Fracture Treatment with Intramedullary Rodding

Background and Objectives: Osteogenesis imperfecta is a rare pathology involving the bones and the connective tissues, generating alterations that lead to frequent fractures during childhood. When fractures occur at birth, they are associated with an impairment of walking and the quality of life. Al...

Descripción completa

Detalles Bibliográficos
Autores principales: Herdea, Alexandru, Ulici, Alexandru, Qirjako, Dimitra, Toma, Alexandra, Derihaci, Răzvan Petru, Lungu, Claudiu N., Charkaoui, Adham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618628/
https://www.ncbi.nlm.nih.gov/pubmed/34828779
http://dx.doi.org/10.3390/children8111066
_version_ 1784604793718702080
author Herdea, Alexandru
Ulici, Alexandru
Qirjako, Dimitra
Toma, Alexandra
Derihaci, Răzvan Petru
Lungu, Claudiu N.
Charkaoui, Adham
author_facet Herdea, Alexandru
Ulici, Alexandru
Qirjako, Dimitra
Toma, Alexandra
Derihaci, Răzvan Petru
Lungu, Claudiu N.
Charkaoui, Adham
author_sort Herdea, Alexandru
collection PubMed
description Background and Objectives: Osteogenesis imperfecta is a rare pathology involving the bones and the connective tissues, generating alterations that lead to frequent fractures during childhood. When fractures occur at birth, they are associated with an impairment of walking and the quality of life. Although surgical techniques have significantly improved in recent years, functional outcomes and the quality of life for pediatric patients that benefited from surgical management with telescopic rods have been less evaluated. This study aimed to measure functional results and determine the factors that influence the quality of life for the pediatric population diagnosed with Osteogenesis imperfecta and surgically treated using the telescopic rod approach after suffering a fracture or severe deformity. Materials and Methods: We conducted a cohort study that consisted of 15 patients diagnosed with Osteogenesis imperfecta (average age of 11.6 years). All individuals possessed at least one intramedullary telescopic rod as a result of the surgical treatment. Results: We observed that the pain, both acute and chronic, impairs the quality of life and interferes with daily living activities, for instance, self-care tasks. Conclusions: Osteogenesis imperfecta is associated with a severely damaged level of walking. All of the aspects of the pediatric patient’s daily life activity seem to be affected. Furthermore, these patients, especially those residing in rural areas, have a poor quality of life.
format Online
Article
Text
id pubmed-8618628
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-86186282021-11-27 Evaluating the Functional Outcomes and the Quality of Life for Pediatric Patients with Osteogenesis Imperfecta after Fracture Treatment with Intramedullary Rodding Herdea, Alexandru Ulici, Alexandru Qirjako, Dimitra Toma, Alexandra Derihaci, Răzvan Petru Lungu, Claudiu N. Charkaoui, Adham Children (Basel) Article Background and Objectives: Osteogenesis imperfecta is a rare pathology involving the bones and the connective tissues, generating alterations that lead to frequent fractures during childhood. When fractures occur at birth, they are associated with an impairment of walking and the quality of life. Although surgical techniques have significantly improved in recent years, functional outcomes and the quality of life for pediatric patients that benefited from surgical management with telescopic rods have been less evaluated. This study aimed to measure functional results and determine the factors that influence the quality of life for the pediatric population diagnosed with Osteogenesis imperfecta and surgically treated using the telescopic rod approach after suffering a fracture or severe deformity. Materials and Methods: We conducted a cohort study that consisted of 15 patients diagnosed with Osteogenesis imperfecta (average age of 11.6 years). All individuals possessed at least one intramedullary telescopic rod as a result of the surgical treatment. Results: We observed that the pain, both acute and chronic, impairs the quality of life and interferes with daily living activities, for instance, self-care tasks. Conclusions: Osteogenesis imperfecta is associated with a severely damaged level of walking. All of the aspects of the pediatric patient’s daily life activity seem to be affected. Furthermore, these patients, especially those residing in rural areas, have a poor quality of life. MDPI 2021-11-19 /pmc/articles/PMC8618628/ /pubmed/34828779 http://dx.doi.org/10.3390/children8111066 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Herdea, Alexandru
Ulici, Alexandru
Qirjako, Dimitra
Toma, Alexandra
Derihaci, Răzvan Petru
Lungu, Claudiu N.
Charkaoui, Adham
Evaluating the Functional Outcomes and the Quality of Life for Pediatric Patients with Osteogenesis Imperfecta after Fracture Treatment with Intramedullary Rodding
title Evaluating the Functional Outcomes and the Quality of Life for Pediatric Patients with Osteogenesis Imperfecta after Fracture Treatment with Intramedullary Rodding
title_full Evaluating the Functional Outcomes and the Quality of Life for Pediatric Patients with Osteogenesis Imperfecta after Fracture Treatment with Intramedullary Rodding
title_fullStr Evaluating the Functional Outcomes and the Quality of Life for Pediatric Patients with Osteogenesis Imperfecta after Fracture Treatment with Intramedullary Rodding
title_full_unstemmed Evaluating the Functional Outcomes and the Quality of Life for Pediatric Patients with Osteogenesis Imperfecta after Fracture Treatment with Intramedullary Rodding
title_short Evaluating the Functional Outcomes and the Quality of Life for Pediatric Patients with Osteogenesis Imperfecta after Fracture Treatment with Intramedullary Rodding
title_sort evaluating the functional outcomes and the quality of life for pediatric patients with osteogenesis imperfecta after fracture treatment with intramedullary rodding
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618628/
https://www.ncbi.nlm.nih.gov/pubmed/34828779
http://dx.doi.org/10.3390/children8111066
work_keys_str_mv AT herdeaalexandru evaluatingthefunctionaloutcomesandthequalityoflifeforpediatricpatientswithosteogenesisimperfectaafterfracturetreatmentwithintramedullaryrodding
AT ulicialexandru evaluatingthefunctionaloutcomesandthequalityoflifeforpediatricpatientswithosteogenesisimperfectaafterfracturetreatmentwithintramedullaryrodding
AT qirjakodimitra evaluatingthefunctionaloutcomesandthequalityoflifeforpediatricpatientswithosteogenesisimperfectaafterfracturetreatmentwithintramedullaryrodding
AT tomaalexandra evaluatingthefunctionaloutcomesandthequalityoflifeforpediatricpatientswithosteogenesisimperfectaafterfracturetreatmentwithintramedullaryrodding
AT derihacirazvanpetru evaluatingthefunctionaloutcomesandthequalityoflifeforpediatricpatientswithosteogenesisimperfectaafterfracturetreatmentwithintramedullaryrodding
AT lunguclaudiun evaluatingthefunctionaloutcomesandthequalityoflifeforpediatricpatientswithosteogenesisimperfectaafterfracturetreatmentwithintramedullaryrodding
AT charkaouiadham evaluatingthefunctionaloutcomesandthequalityoflifeforpediatricpatientswithosteogenesisimperfectaafterfracturetreatmentwithintramedullaryrodding