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Long-Term Symptoms among Hospitalized COVID-19 Patients 48 Weeks after Discharge—A Prospective Cohort Study

Follow-up studies of COVID-19 survivors have been performed to characterize persistence of long-term symptoms, but data are scarce on one year of follow-up. This study provides data from 48 weeks of follow-up after discharge. All patients discharged from the Department of Infectious Diseases at Aarh...

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Autores principales: Mølhave, Martin, Leth, Steffen, Gunst, Jesper Damsgaard, Jensen-Fangel, Søren, Østergaard, Lars, Wejse, Christian, Agergaard, Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618663/
https://www.ncbi.nlm.nih.gov/pubmed/34830580
http://dx.doi.org/10.3390/jcm10225298
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author Mølhave, Martin
Leth, Steffen
Gunst, Jesper Damsgaard
Jensen-Fangel, Søren
Østergaard, Lars
Wejse, Christian
Agergaard, Jane
author_facet Mølhave, Martin
Leth, Steffen
Gunst, Jesper Damsgaard
Jensen-Fangel, Søren
Østergaard, Lars
Wejse, Christian
Agergaard, Jane
author_sort Mølhave, Martin
collection PubMed
description Follow-up studies of COVID-19 survivors have been performed to characterize persistence of long-term symptoms, but data are scarce on one year of follow-up. This study provides data from 48 weeks of follow-up after discharge. All patients discharged from the Department of Infectious Diseases at Aarhus University Hospital, Denmark between 1 March and 1 July 2020 were followed for 48 weeks. In total, 45 of 66 eligible patients were interviewed after 48 weeks. The median age was 57 (IQR 51–70) years, the majority were female (53%) and Caucasian (87%). Median BMI was 28.1 (IQR 24.8–32.6) kg/m(2). One or more comorbidities were registered among 62% of the patients. In total, 39 out of 45 (87%) interviewed patients reported persistence of at least one symptom 48 weeks after hospitalization with COVID-19. Most frequently reported symptoms were fatigue, dyspnea, and concentration difficulties. This study provides new long-term data following COVID-19, contributing to the accumulating data of COVID-19 sequelae. Many patients suffer long-term sequelae and further research is urgently needed to gain further knowledge of the duration and therapeutic options.
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spelling pubmed-86186632021-11-27 Long-Term Symptoms among Hospitalized COVID-19 Patients 48 Weeks after Discharge—A Prospective Cohort Study Mølhave, Martin Leth, Steffen Gunst, Jesper Damsgaard Jensen-Fangel, Søren Østergaard, Lars Wejse, Christian Agergaard, Jane J Clin Med Brief Report Follow-up studies of COVID-19 survivors have been performed to characterize persistence of long-term symptoms, but data are scarce on one year of follow-up. This study provides data from 48 weeks of follow-up after discharge. All patients discharged from the Department of Infectious Diseases at Aarhus University Hospital, Denmark between 1 March and 1 July 2020 were followed for 48 weeks. In total, 45 of 66 eligible patients were interviewed after 48 weeks. The median age was 57 (IQR 51–70) years, the majority were female (53%) and Caucasian (87%). Median BMI was 28.1 (IQR 24.8–32.6) kg/m(2). One or more comorbidities were registered among 62% of the patients. In total, 39 out of 45 (87%) interviewed patients reported persistence of at least one symptom 48 weeks after hospitalization with COVID-19. Most frequently reported symptoms were fatigue, dyspnea, and concentration difficulties. This study provides new long-term data following COVID-19, contributing to the accumulating data of COVID-19 sequelae. Many patients suffer long-term sequelae and further research is urgently needed to gain further knowledge of the duration and therapeutic options. MDPI 2021-11-15 /pmc/articles/PMC8618663/ /pubmed/34830580 http://dx.doi.org/10.3390/jcm10225298 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Brief Report
Mølhave, Martin
Leth, Steffen
Gunst, Jesper Damsgaard
Jensen-Fangel, Søren
Østergaard, Lars
Wejse, Christian
Agergaard, Jane
Long-Term Symptoms among Hospitalized COVID-19 Patients 48 Weeks after Discharge—A Prospective Cohort Study
title Long-Term Symptoms among Hospitalized COVID-19 Patients 48 Weeks after Discharge—A Prospective Cohort Study
title_full Long-Term Symptoms among Hospitalized COVID-19 Patients 48 Weeks after Discharge—A Prospective Cohort Study
title_fullStr Long-Term Symptoms among Hospitalized COVID-19 Patients 48 Weeks after Discharge—A Prospective Cohort Study
title_full_unstemmed Long-Term Symptoms among Hospitalized COVID-19 Patients 48 Weeks after Discharge—A Prospective Cohort Study
title_short Long-Term Symptoms among Hospitalized COVID-19 Patients 48 Weeks after Discharge—A Prospective Cohort Study
title_sort long-term symptoms among hospitalized covid-19 patients 48 weeks after discharge—a prospective cohort study
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618663/
https://www.ncbi.nlm.nih.gov/pubmed/34830580
http://dx.doi.org/10.3390/jcm10225298
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