Protective Efficacy in a Hamster Model of a Multivalent Vaccine for Human Visceral Leishmaniasis (MuLeVaClin) Consisting of the KMP11, LEISH-F3+, and LJL143 Antigens in Virosomes, Plus GLA-SE Adjuvant

Visceral leishmaniasis (VL) is the most severe clinical form of leishmaniasis, fatal if untreated. Vaccination is the most cost-effective approach to disease control; however, to date, no vaccines against human VL have been made available. This work examines the efficacy of a novel vaccine consistin...

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Detalles Bibliográficos
Autores principales: Fernández, Laura, Solana, Jose Carlos, Sánchez, Carmen, Jiménez, Mª Ángeles, Requena, Jose M., Coler, Rhea, Reed, Steven G., Valenzuela, Jesus G., Kamhawi, Shaden, Oliveira, Fabiano, Fichera, Epifanio, Glueck, Reinhard, Bottazzi, Maria Elena, Gupta, Gaurav, Cecilio, Pedro, Pérez-Cabezas, Begoña, Cordeiro-da-Silva, Anabela, Gradoni, Luigi, Carrillo, Eugenia, Moreno, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618729/
https://www.ncbi.nlm.nih.gov/pubmed/34835379
http://dx.doi.org/10.3390/microorganisms9112253

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