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Phytosterols: Potential Metabolic Modulators in Neurodegenerative Diseases
Phytosterols constitute a class of natural products that are an important component of diet and have vast applications in foods, cosmetics, and herbal medicines. With many and diverse isolated structures in nature, they exhibit a broad range of biological and pharmacological activities. Among over 2...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618769/ https://www.ncbi.nlm.nih.gov/pubmed/34830148 http://dx.doi.org/10.3390/ijms222212255 |
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author | Sharma, Niti Tan, Mario A. An, Seong Soo A. |
author_facet | Sharma, Niti Tan, Mario A. An, Seong Soo A. |
author_sort | Sharma, Niti |
collection | PubMed |
description | Phytosterols constitute a class of natural products that are an important component of diet and have vast applications in foods, cosmetics, and herbal medicines. With many and diverse isolated structures in nature, they exhibit a broad range of biological and pharmacological activities. Among over 200 types of phytosterols, stigmasterol and β-sitosterol were ubiquitous in many plant species, exhibiting important aspects of activities related to neurodegenerative diseases. Hence, this mini-review presented an overview of the reported studies on selected phytosterols related to neurodegenerative diseases. It covered the major phytosterols based on biosynthetic considerations, including other phytosterols with significant in vitro and in vivo biological activities. |
format | Online Article Text |
id | pubmed-8618769 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-86187692021-11-27 Phytosterols: Potential Metabolic Modulators in Neurodegenerative Diseases Sharma, Niti Tan, Mario A. An, Seong Soo A. Int J Mol Sci Review Phytosterols constitute a class of natural products that are an important component of diet and have vast applications in foods, cosmetics, and herbal medicines. With many and diverse isolated structures in nature, they exhibit a broad range of biological and pharmacological activities. Among over 200 types of phytosterols, stigmasterol and β-sitosterol were ubiquitous in many plant species, exhibiting important aspects of activities related to neurodegenerative diseases. Hence, this mini-review presented an overview of the reported studies on selected phytosterols related to neurodegenerative diseases. It covered the major phytosterols based on biosynthetic considerations, including other phytosterols with significant in vitro and in vivo biological activities. MDPI 2021-11-12 /pmc/articles/PMC8618769/ /pubmed/34830148 http://dx.doi.org/10.3390/ijms222212255 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Sharma, Niti Tan, Mario A. An, Seong Soo A. Phytosterols: Potential Metabolic Modulators in Neurodegenerative Diseases |
title | Phytosterols: Potential Metabolic Modulators in Neurodegenerative Diseases |
title_full | Phytosterols: Potential Metabolic Modulators in Neurodegenerative Diseases |
title_fullStr | Phytosterols: Potential Metabolic Modulators in Neurodegenerative Diseases |
title_full_unstemmed | Phytosterols: Potential Metabolic Modulators in Neurodegenerative Diseases |
title_short | Phytosterols: Potential Metabolic Modulators in Neurodegenerative Diseases |
title_sort | phytosterols: potential metabolic modulators in neurodegenerative diseases |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618769/ https://www.ncbi.nlm.nih.gov/pubmed/34830148 http://dx.doi.org/10.3390/ijms222212255 |
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