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Phytosterols: Potential Metabolic Modulators in Neurodegenerative Diseases

Phytosterols constitute a class of natural products that are an important component of diet and have vast applications in foods, cosmetics, and herbal medicines. With many and diverse isolated structures in nature, they exhibit a broad range of biological and pharmacological activities. Among over 2...

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Detalles Bibliográficos
Autores principales: Sharma, Niti, Tan, Mario A., An, Seong Soo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618769/
https://www.ncbi.nlm.nih.gov/pubmed/34830148
http://dx.doi.org/10.3390/ijms222212255
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author Sharma, Niti
Tan, Mario A.
An, Seong Soo A.
author_facet Sharma, Niti
Tan, Mario A.
An, Seong Soo A.
author_sort Sharma, Niti
collection PubMed
description Phytosterols constitute a class of natural products that are an important component of diet and have vast applications in foods, cosmetics, and herbal medicines. With many and diverse isolated structures in nature, they exhibit a broad range of biological and pharmacological activities. Among over 200 types of phytosterols, stigmasterol and β-sitosterol were ubiquitous in many plant species, exhibiting important aspects of activities related to neurodegenerative diseases. Hence, this mini-review presented an overview of the reported studies on selected phytosterols related to neurodegenerative diseases. It covered the major phytosterols based on biosynthetic considerations, including other phytosterols with significant in vitro and in vivo biological activities.
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spelling pubmed-86187692021-11-27 Phytosterols: Potential Metabolic Modulators in Neurodegenerative Diseases Sharma, Niti Tan, Mario A. An, Seong Soo A. Int J Mol Sci Review Phytosterols constitute a class of natural products that are an important component of diet and have vast applications in foods, cosmetics, and herbal medicines. With many and diverse isolated structures in nature, they exhibit a broad range of biological and pharmacological activities. Among over 200 types of phytosterols, stigmasterol and β-sitosterol were ubiquitous in many plant species, exhibiting important aspects of activities related to neurodegenerative diseases. Hence, this mini-review presented an overview of the reported studies on selected phytosterols related to neurodegenerative diseases. It covered the major phytosterols based on biosynthetic considerations, including other phytosterols with significant in vitro and in vivo biological activities. MDPI 2021-11-12 /pmc/articles/PMC8618769/ /pubmed/34830148 http://dx.doi.org/10.3390/ijms222212255 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Sharma, Niti
Tan, Mario A.
An, Seong Soo A.
Phytosterols: Potential Metabolic Modulators in Neurodegenerative Diseases
title Phytosterols: Potential Metabolic Modulators in Neurodegenerative Diseases
title_full Phytosterols: Potential Metabolic Modulators in Neurodegenerative Diseases
title_fullStr Phytosterols: Potential Metabolic Modulators in Neurodegenerative Diseases
title_full_unstemmed Phytosterols: Potential Metabolic Modulators in Neurodegenerative Diseases
title_short Phytosterols: Potential Metabolic Modulators in Neurodegenerative Diseases
title_sort phytosterols: potential metabolic modulators in neurodegenerative diseases
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618769/
https://www.ncbi.nlm.nih.gov/pubmed/34830148
http://dx.doi.org/10.3390/ijms222212255
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