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Actinomycin V Induces Apoptosis Associated with Mitochondrial and PI3K/AKT Pathways in Human CRC Cells

Actinomycin (Act) V, an analogue of Act D, presented stronger antitumor activity and less hepatorenal toxicity than Act D in our previous studies, which is worthy of further investigation. We hereby report that Act V induces apoptosis via mitochondrial and PI3K/AKT pathways in colorectal cancer (CRC...

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Detalles Bibliográficos
Autores principales:	Jiang, Shiqing, Zhang, E, Ruan, Hang, Ma, Jiahui, Zhao, Xingming, Zhu, Yaoyao, Xie, Xiaoyu, Han, Ningning, Li, Jianjiang, Zhang, Hao, Xie, Weidong, Li, Xia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618951/ https://www.ncbi.nlm.nih.gov/pubmed/34822470 http://dx.doi.org/10.3390/md19110599

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