Cargando…

Predictors of Atrial Fibrillation Recurrences after a First Radiofrequency Catheter Ablation Intervention for Paroxysmal Atrial Fibrillation—Experience of a Low Volume Ablation Centre

Background and Objectives: Atrial fibrillation recurrences (AFR) after radiofrequency catheter ablation (RFCA) are not uncommon, up to 65% of patients having relapses in the first year. However, current data are based mainly on studies from centres with a large volume of ablations, as they include t...

Descripción completa

Detalles Bibliográficos
Autores principales: Matei, Lavinia-Lucia, Siliște, Călin, Stoica, Sebastian, Bejan, Gabriel-Cristian, Ghilencea, Liviu-Nicolae, Vinereanu, Dragoș
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618952/
https://www.ncbi.nlm.nih.gov/pubmed/34833357
http://dx.doi.org/10.3390/medicina57111139
_version_ 1784604872279064576
author Matei, Lavinia-Lucia
Siliște, Călin
Stoica, Sebastian
Bejan, Gabriel-Cristian
Ghilencea, Liviu-Nicolae
Vinereanu, Dragoș
author_facet Matei, Lavinia-Lucia
Siliște, Călin
Stoica, Sebastian
Bejan, Gabriel-Cristian
Ghilencea, Liviu-Nicolae
Vinereanu, Dragoș
author_sort Matei, Lavinia-Lucia
collection PubMed
description Background and Objectives: Atrial fibrillation recurrences (AFR) after radiofrequency catheter ablation (RFCA) are not uncommon, up to 65% of patients having relapses in the first year. However, current data are based mainly on studies from centres with a large volume of ablations, as they include technically inhomogeneous interventions, and populations with different types of AF. The aim of our study was to assess and stratify the risk at 6 and 12 months for AFR after a single RFCA, in patients with paroxysmal AF, in a centre with low volume activity. Materials and Methods: We enrolled 40 patients who underwent an initial RFCA, followed by continuous 48 h ECG monitoring at 1, 3, 6, and 12 months. Patients self-monitored their cardiac activity by random daily radial pulse palpation or in the presence of palpitations. Results: Ten independent predictors for late AFR were identified, and a 6-month risk score was computed using three of them: AFR duration in the first month, number of AFR between 1 and 3 months, and supraventricular ectopics per 24 h at 6 months. The score can explain 59% of the AFR (p = 0.001). A further 12-month assessment identified three independent predictors. The presence of AFR between 6–12 months is the most important of them (OR = 23.11, 95% CI = 3.87–137.83, p = 0.001), explaining 45% of AFR over 1 year. The risk scores at 6 and 12 months were internally validated. Conclusions: The 6-month score proved to be a useful tool in guiding further strategy for patients with a low risk, while a longer follow-up to 12 months may avoid unnecessary early reinterventions.
format Online
Article
Text
id pubmed-8618952
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-86189522021-11-27 Predictors of Atrial Fibrillation Recurrences after a First Radiofrequency Catheter Ablation Intervention for Paroxysmal Atrial Fibrillation—Experience of a Low Volume Ablation Centre Matei, Lavinia-Lucia Siliște, Călin Stoica, Sebastian Bejan, Gabriel-Cristian Ghilencea, Liviu-Nicolae Vinereanu, Dragoș Medicina (Kaunas) Article Background and Objectives: Atrial fibrillation recurrences (AFR) after radiofrequency catheter ablation (RFCA) are not uncommon, up to 65% of patients having relapses in the first year. However, current data are based mainly on studies from centres with a large volume of ablations, as they include technically inhomogeneous interventions, and populations with different types of AF. The aim of our study was to assess and stratify the risk at 6 and 12 months for AFR after a single RFCA, in patients with paroxysmal AF, in a centre with low volume activity. Materials and Methods: We enrolled 40 patients who underwent an initial RFCA, followed by continuous 48 h ECG monitoring at 1, 3, 6, and 12 months. Patients self-monitored their cardiac activity by random daily radial pulse palpation or in the presence of palpitations. Results: Ten independent predictors for late AFR were identified, and a 6-month risk score was computed using three of them: AFR duration in the first month, number of AFR between 1 and 3 months, and supraventricular ectopics per 24 h at 6 months. The score can explain 59% of the AFR (p = 0.001). A further 12-month assessment identified three independent predictors. The presence of AFR between 6–12 months is the most important of them (OR = 23.11, 95% CI = 3.87–137.83, p = 0.001), explaining 45% of AFR over 1 year. The risk scores at 6 and 12 months were internally validated. Conclusions: The 6-month score proved to be a useful tool in guiding further strategy for patients with a low risk, while a longer follow-up to 12 months may avoid unnecessary early reinterventions. MDPI 2021-10-20 /pmc/articles/PMC8618952/ /pubmed/34833357 http://dx.doi.org/10.3390/medicina57111139 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Matei, Lavinia-Lucia
Siliște, Călin
Stoica, Sebastian
Bejan, Gabriel-Cristian
Ghilencea, Liviu-Nicolae
Vinereanu, Dragoș
Predictors of Atrial Fibrillation Recurrences after a First Radiofrequency Catheter Ablation Intervention for Paroxysmal Atrial Fibrillation—Experience of a Low Volume Ablation Centre
title Predictors of Atrial Fibrillation Recurrences after a First Radiofrequency Catheter Ablation Intervention for Paroxysmal Atrial Fibrillation—Experience of a Low Volume Ablation Centre
title_full Predictors of Atrial Fibrillation Recurrences after a First Radiofrequency Catheter Ablation Intervention for Paroxysmal Atrial Fibrillation—Experience of a Low Volume Ablation Centre
title_fullStr Predictors of Atrial Fibrillation Recurrences after a First Radiofrequency Catheter Ablation Intervention for Paroxysmal Atrial Fibrillation—Experience of a Low Volume Ablation Centre
title_full_unstemmed Predictors of Atrial Fibrillation Recurrences after a First Radiofrequency Catheter Ablation Intervention for Paroxysmal Atrial Fibrillation—Experience of a Low Volume Ablation Centre
title_short Predictors of Atrial Fibrillation Recurrences after a First Radiofrequency Catheter Ablation Intervention for Paroxysmal Atrial Fibrillation—Experience of a Low Volume Ablation Centre
title_sort predictors of atrial fibrillation recurrences after a first radiofrequency catheter ablation intervention for paroxysmal atrial fibrillation—experience of a low volume ablation centre
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618952/
https://www.ncbi.nlm.nih.gov/pubmed/34833357
http://dx.doi.org/10.3390/medicina57111139
work_keys_str_mv AT mateilavinialucia predictorsofatrialfibrillationrecurrencesafterafirstradiofrequencycatheterablationinterventionforparoxysmalatrialfibrillationexperienceofalowvolumeablationcentre
AT silistecalin predictorsofatrialfibrillationrecurrencesafterafirstradiofrequencycatheterablationinterventionforparoxysmalatrialfibrillationexperienceofalowvolumeablationcentre
AT stoicasebastian predictorsofatrialfibrillationrecurrencesafterafirstradiofrequencycatheterablationinterventionforparoxysmalatrialfibrillationexperienceofalowvolumeablationcentre
AT bejangabrielcristian predictorsofatrialfibrillationrecurrencesafterafirstradiofrequencycatheterablationinterventionforparoxysmalatrialfibrillationexperienceofalowvolumeablationcentre
AT ghilencealiviunicolae predictorsofatrialfibrillationrecurrencesafterafirstradiofrequencycatheterablationinterventionforparoxysmalatrialfibrillationexperienceofalowvolumeablationcentre
AT vinereanudragos predictorsofatrialfibrillationrecurrencesafterafirstradiofrequencycatheterablationinterventionforparoxysmalatrialfibrillationexperienceofalowvolumeablationcentre