Ischemia/Reperfusion Injury of Fatty Liver Is Protected by A2AR and Exacerbated by A1R Stimulation through Opposite Effects on ASK1 Activation

Hepatic ischemia/reperfusion injury (IRI) is aggravated by steatosis and is a main risk factor in fatty liver transplantation. Adenosine receptors (ARs) are emerging as therapeutic targets in liver diseases. By using cellular and in vivo systems of hepatic steatosis and IRI, here we evaluated the ef...

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Detalles Bibliográficos
Autores principales: Alchera, Elisa, Chandrashekar, Bangalore R., Clemente, Nausicaa, Borroni, Ester, Boldorini, Renzo, Carini, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8618984/
https://www.ncbi.nlm.nih.gov/pubmed/34831394
http://dx.doi.org/10.3390/cells10113171

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