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Development of a SARS-CoV-2 Vaccine Candidate Using Plant-Based Manufacturing and a Tobacco Mosaic Virus-Like Nano-Particle
Stable, effective, easy-to-manufacture vaccines are critical to stopping the COVID-19 pandemic resulting from the coronavirus SARS-CoV-2. We constructed a vaccine candidate CoV-RBD121-NP, which is comprised of the SARS-CoV-2 receptor-binding domain (RBD) of the spike glycoprotein (S) fused to a huma...
Autores principales: | Royal, Joshua M., Simpson, Carrie A., McCormick, Alison A., Phillips, Amanda, Hume, Steve, Morton, Josh, Shepherd, John, Oh, Youngjun, Swope, Kelsi, DeBeauchamp, Jennifer L., Webby, Richard J., Cross, Robert W., Borisevich, Viktoriya, Geisbert, Thomas W., Demarco, Jennifer K., Bratcher, Barry, Haydon, Hugh, Pogue, Gregory P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619098/ https://www.ncbi.nlm.nih.gov/pubmed/34835278 http://dx.doi.org/10.3390/vaccines9111347 |
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